EEG Amplifier Synchronization via Low-Frequency Signal

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Solution Overview

Problem

Current EEG monitoring systems face challenges in synchronizing multiple amplifiers effectively, leading to errors and interference from electromagnetic noise, particularly due to the need for high-speed clock distribution and specialized components, which are costly and prone to interference.

Innovation Solution

A system and method utilizing a low frequency synchronizing signal shared among amplifiers, using voltage-controlled oscillators and microcontrollers to adjust frequencies, eliminating the need for high-speed clock distribution and reducing electromagnetic interference through single-ended circuitry and cabling.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If high-speed clock distribution is used to synchronize multiple amplifiers, then synchronization accuracy is improved, but electromagnetic interference and system complexity increase

Engineering Contradiction:
Improvesynchronization accuracyVSAvoidelectromagnetic interference
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The patent changes the frequency parameter of the synchronizing signal from high-speed to low-speed (e.g., 1 Hz). This parameter change maintains synchronization accuracy for EEG data acquisition while dramatically reducing electromagnetic interference and allowing the use of simple single-ended circuitry instead of complex differential signaling

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent replaces expensive, specialized components (temperature-controlled oscillators, differential circuitry, shielded cables) with inexpensive, standard components (low-frequency oscillators, single-ended circuitry, ordinary cables). This substitution achieves the same synchronization function without the harmful effects of high-speed signals

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

2Reliability

If specialized temperature-controlled oscillators are used for synchronization, then reliability is improved, but cost and power consumption increase

Engineering Contradiction:
Improvesynchronization reliabilityVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent changes the operating frequency parameter to low-frequency (e.g., 1 Hz), which allows standard voltage-controlled oscillators to achieve sufficient stability without requiring complex temperature control mechanisms. This parameter change fundamentally alters the design requirements from high-precision frequency stability to adequate low-frequency stability

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent uses a simple low-frequency square wave signal as a copy or replacement for complex high-speed clock signals. This simplified synchronizing signal carries the necessary timing information for EEG acquisition without requiring the complexity of high-speed oscillators and their associated control systems

Inventive Principle:
Principle #26Copying

3Measurement precision

If high-speed clock signals are distributed among amplifiers, then data synchronization is improved, but electromagnetic interference and noise increase

Engineering Contradiction:
Improvedata synchronizationVSAvoidbeat frequency noise
Core Design Contradiction:
Measurement precisionVSObject-generated harmful factors

Solution Approach 1:

The patent changes the frequency parameter from high-speed to low-speed (1 Hz), which eliminates beat frequency noise generation. At such low frequencies, the amplifiers' ADCs can still be synchronized effectively for EEG data acquisition without creating the high-frequency interference that causes beat noise

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent extracts only the essential timing function from the high-speed clock signal, implementing it through a separate low-frequency synchronizing signal. This separation allows the ADCs to be triggered in unison without requiring the continuous presence of high-speed clock signals in the amplifier chains, thereby eliminating the source of electromagnetic interference and beat frequency noise

Inventive Principle:
Principle #2Taking out (Extraction)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach simplifies data synchronization, reduces costs, and minimizes electromagnetic interference, ensuring accurate and reliable synchronization of EEG signals across multiple amplifiers, thereby improving the accuracy of brain activity monitoring.

Implementation Method 1

a voltage-controlled oscillator; adjusting a frequency of the voltage-controlled oscillator based on the synchronizing signal

Methodology Applied
Scientific EffectVoltage-controlled oscillation:

Data Source

PatentUS20230157620A1Method and System for Data Synchronization
Publication Date: 2023.05.25 CADWELL LAB INC
  • US20230157620A1 patent drawing
  • US20230157620A1 patent drawing
  • US20230157620A1 patent drawing

AI summary

A system for monitoring includes: multiple EEG sensors spatially positioned on a layer of tissue for capturing EEG signals of a patient; multiple amplifiers coupled with the EEG sensors for amplifying the captured signals; and a low frequency oscillator for generating a synchronizing signal which is distributed to the amplifiers for synchronizing the digitization of the captured signals; wherein each amplifier includes: a voltage controlled oscillator for an adjustable frequency reference; an analog to digital converter for converting the amplified signal to a digital value; and a microcontroller for controlling the frequency of the voltage controlled oscillator and operation of the analog to digital converter by using the synchronizing signal.