EEG-Based Closed-Loop Neuromodulation for Sensorimotor Learning

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Solution Overview

Problem

Current methods lack an effective way to enhance and assess sensorimotor learning, as they fail to utilize EEG data to tailor learning schedules and provide real-time neuromodulation for improved performance and adaptation.

Innovation Solution

A system combining non-invasive EEG recording and neuromodulation that uses EEG frequencies to assess sensorimotor learning states and capabilities, applying adaptive learning schedules and neuromodulation stimuli to enhance learning through a closed-loop mechanism, driven by both individual and normative data.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If traditional sensorimotor training methods are used, then learning can occur, but learning efficiency and adaptation rate are limited without real-time neural feedback

Engineering Contradiction:
Improvelearning rateVSAvoidlack of real-time neural state information
Core Design Contradiction:
ProductivityVSLoss of information

Solution Approach 1:

The system implements closed-loop feedback by continuously monitoring EEG signals to assess sensorimotor learning states and using this information to adaptively adjust training schedules and deliver real-time neuromodulation stimuli, transforming open-loop traditional training into a dynamic feedback-driven system that optimizes learning efficiency

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The system enables self-regulation of the learning process by using individually tailored adaptive learning schedules that automatically adjust based on real-time EEG assessment of the subject's neural state, allowing the system to self-optimize training parameters without external intervention

Inventive Principle:
Principle #25Self-service

2Adaptability or versatility

If fixed learning schedules are used, then training structure is maintained, but individual learning capabilities and neural states are not accommodated

Engineering Contradiction:
Improvetailoring to individual learning capabilitiesVSAvoidcomplexity of adaptive learning schedule system
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The learning schedule transitions from a static fixed structure to a dynamic adaptive system that continuously adjusts training parameters based on real-time EEG assessment of neural oscillations and sensorimotor learning states, enabling the system to flexibly respond to individual learning capabilities

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system dynamically modifies training schedule parameters including task difficulty, inter-trial intervals, and stimulation timing based on quantitative EEG metrics such as beta band power and event-related spectral perturbations, allowing adaptation to individual learning rates without requiring complex manual programming

Inventive Principle:
Principle #35Parameter changes

3Reliability

If EEG-based adaptive control is implemented, then learning enhancement is achieved, but system complexity and computational requirements increase

Engineering Contradiction:
Improveassessment accuracy of sensorimotor learning statesVSAvoidcomplexity of EEG decoding and neuromodulation system
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The system extracts specific informative features from complex EEG signals, focusing on key oscillatory bands (alpha, beta, gamma) and event-related components that are most predictive of sensorimotor learning states, thereby simplifying the control problem while maintaining high assessment accuracy

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The system employs machine learning classifiers and computational models as intermediaries that translate raw EEG signals into interpretable neural state assessments and control commands, bridging the gap between complex neural data and actionable training adjustments without requiring direct complex processing of all EEG features

Inventive Principle:
Principle #24Intermediary (Mediator)

4Productivity

If neuromodulation stimuli are applied, then sensorimotor function is enhanced, but energy consumption and stimulation precision requirements increase

Engineering Contradiction:
Improvesensorimotor learning efficiencyVSAvoidprecision of neuromodulation stimulus timing and frequency
Core Design Contradiction:
ProductivityVSManufacturing precision

Solution Approach 1:

The system applies periodic neuromodulation stimuli synchronized to naturally occurring neural oscillations identified through EEG, using rhythmic stimulation at specific frequencies (e.g., beta band) to resonantly enhance sensorimotor processing and learning efficiency through frequency-specific neuromodulation

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

The system delivers neuromodulation stimuli at optimally timed moments based on real-time EEG assessment of neural readiness states, applying stimulation in advance of critical learning moments to prime neural circuits for enhanced plasticity and learning before tasks are performed

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS10932688B2EEG-based decoding and closed-loop neuromodulation system for assessing and enhancing sensorimotor learning
Publication Date: 2021.03.02 THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIV OF ARIZONA
  • US10932688B2 patent drawing
  • US10932688B2 patent drawing

AI summary

Systems and methods are described for enhancing sensorimotor learning using EEG decoding and closed-loop neuromodulation. A plurality of EEG electrodes and a plurality of stimulation electrodes are coupled to a learning subject. An output device of an adaptive learning system provides a sequence of instructions to the learning subject for performing a sensorimotor task in accordance with a defined learning schedule. The defined learning schedule is adjusted based on a monitored EEG signal while performing the task and, in some implementations, a neuromodulation stimulus signal is applied to the learning subject that is designed to cause the monitored EEG signal of the learning subject to approach at least one target EEG signal parameter.