EEG-guided spatial neglect detection using neural markers

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Solution Overview

Problem

Current methods for assessing visual spatial neglect (SN) in stroke patients are insufficient, as they fail to accurately measure the extent of neglect and do not account for compensatory strategies or dynamic real-life environments.

Innovation Solution

A method and system that utilize electroencephalography (EEG) and augmented reality (AR) to determine the extent of visual spatial neglect. The system includes a presentation apparatus with an AR display and an EEG apparatus, which collect data during a software-based test. This data is then analyzed to provide an indication of the extent of neglect.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional pen-and-paper tests (BIT-C) are used to assess spatial neglect, then the assessment is simple and inexpensive, but the measurement precision is insufficient and cannot accurately measure the extent of neglect

Engineering Contradiction:
Improveaccuracy of neglect assessmentVSAvoidcomplexity of assessment system
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent replaces conventional mechanical pen-and-paper testing with a computerized system that uses EEG (electroencephalography) to detect brain activity patterns. The EEG-based computerized assessment substitutes the mechanical interaction of writing and paper with electrical signal detection and digital processing, enabling more precise measurement of spatial neglect extent through objective neural markers rather than subjective behavioral observations.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent introduces EEG technology as an intermediary between the patient's neural processing and the assessment measurement. The EEG system serves as a mediator that captures brain activity patterns related to spatial attention and translates them into quantifiable data about neglect extent, providing an objective intermediate measure that bridges the gap between neural function and behavioral assessment.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If computerized methods are used to improve sensitivity in detecting SN, then measurement precision improves, but the device complexity increases

Engineering Contradiction:
Improvesensitivity of SN detectionVSAvoidcomplexity of computerized assessment system
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent replaces complex computerized visual attention tasks with a simpler EEG-based detection system. Instead of requiring sophisticated computerized stimuli presentation and response tracking, the system uses EEG to directly detect neural markers of spatial neglect, substituting mechanical computer interaction with electrical signal measurement that is inherently more sensitive to subtle attentional deficits.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The EEG-based system performs self-detection of spatial neglect markers without requiring complex external stimulation protocols. The system leverages the patient's own brain activity patterns during natural or simplified tasks, allowing the assessment to emerge from the patient's intrinsic neural responses rather than requiring elaborate external testing apparatus.

Inventive Principle:
Principle #25Self-service

3Adaptability or versatility

If traditional assessment methods are used, then the ease of operation is high, but the adaptability to dynamic real-life environments is poor

Engineering Contradiction:
Improveadaptability to dynamic environmentsVSAvoidsimplicity of assessment administration
Core Design Contradiction:
Adaptability or versatilityVSEase of operation

Solution Approach 1:

The patent introduces dynamic elements into the assessment by using EEG to capture real-time brain activity patterns during spatial attention tasks. The system can adapt to varying environmental conditions and patient states by continuously monitoring neural markers, allowing the assessment to remain valid across different contexts and dynamic situations rather than being fixed to static testing conditions.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The EEG-based system allows for parameter changes in the assessment by adjusting EEG recording parameters, analysis methods, and interpretation criteria based on environmental context and patient characteristics. This enables the same core technology to adapt to different testing environments, patient populations, and clinical scenarios without requiring fundamentally different assessment tools.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system provides a more accurate and reliable assessment of visual spatial neglect by accounting for compensatory strategies and dynamic environments, enabling better targeted rehabilitation plans.

Implementation Method 1

collecting EEG information during the test via an EEG apparatus positioned on the head of the patient

Methodology Applied
Scientific EffectElectroencephalography (EEG):

Data Source

PatentUS20250032044A1EEG-guided spatial neglect detection system and detection method employing same
Publication Date: 2025.01.30 UNIV OF PITTSBURGH OF THE COMMONWEALTH SYST OF HIGHER EDUCATION
  • US20250032044A1 patent drawing
  • US20250032044A1 patent drawing
  • US20250032044A1 patent drawing

AI summary

A method of determining an extent of visual spatial neglect of a patient includes providing a software-based test to the patient via a presentation apparatus positioned on the head of the patient and having a display device positioned close and in front of the eyes of the patient. EEG information is collected from the patient during the test via an EEG apparatus positioned on the head of the patient. Portions of the EEG information collected during the test are used to determine the extent of the visual spatial neglect of the patient. An indication of the extent of the visual spatial neglect of the patient is provided.