EEG-Guided Transcranial Stimulation for Brain Injury Assessment

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current methods for assessing and diagnosing traumatic brain injuries and related disorders, such as PTSD and neurodegenerative conditions, are costly, inefficient, and prone to false negatives, lacking the resolution and sensitivity to accurately identify functional brain capacity and provide effective treatment interventions.

Innovation Solution

A transcranial stimulation device and machine learning system that uses non-invasive electrodes to measure brain electrical activity, administer targeted electrical stimulation, and integrate physiological data to determine brain malady types and severity, generating personalized treatment protocols through machine learning algorithms.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If non-invasive electrical assessment methodologies are used to diagnose brain injuries, then the assessment can be performed quickly and portably, but the resolution and sensitivity are insufficient to accurately identify functional brain capacity

Engineering Contradiction:
Improveassessment speedVSAvoidbrain function detection sensitivity
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The patent combines multiple assessment modalities including electrophysiological testing (EEG), transcranial stimulation (tDCS/TMS), and machine learning analysis into a single integrated system. This merging allows the device to maintain portability and speed while achieving high measurement precision through the synergistic combination of multiple techniques that compensate for individual limitations.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The system incorporates real-time feedback mechanisms where machine learning algorithms continuously analyze electrophysiological data during assessment and adjust stimulation parameters dynamically. This feedback loop enables the device to improve measurement precision iteratively while maintaining rapid assessment capability through automated real-time processing.

Inventive Principle:
Principle #23Feedback

2Measurement precision

If comprehensive electrophysiological testing and machine learning analysis are implemented, then diagnostic accuracy improves, but device complexity and cost increase

Engineering Contradiction:
Improvediagnostic accuracyVSAvoidsystem structure
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The system employs machine learning algorithms that automatically analyze electrophysiological data and generate diagnostic conclusions without requiring complex manual interpretation protocols. The device performs self-calibration and adaptive parameter selection, reducing the need for highly trained operators and simplifying the user interface while maintaining high diagnostic accuracy.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent utilizes variable stimulation parameters (intensity, frequency, duration) that are dynamically adjusted based on real-time electrophysiological feedback and machine learning predictions. By changing parameters adaptively rather than using fixed complex protocols, the system achieves high diagnostic accuracy with a more manageable device architecture.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If personalized treatment protocols are generated through machine learning, then treatment effectiveness improves, but data processing time and computational requirements increase

Engineering Contradiction:
Improvetreatment effectivenessVSAvoidprotocol generation time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The system pre-loads machine learning models and reference databases during device initialization or offline periods, so that when assessment data is collected, the personalized treatment protocol can be generated rapidly by comparing against pre-computed reference cases. This preliminary preparation significantly reduces real-time computational requirements and protocol generation time.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The machine learning system identifies patterns in electrophysiological data that match known treatment-responsive profiles from training data, allowing it to generate personalized protocols by adapting proven treatment patterns rather than computing entirely new protocols from scratch. This copying approach maintains treatment effectiveness while reducing computational time.

Inventive Principle:
Principle #26Copying

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Provides rapid, accurate assessment and treatment of brain injuries and disorders by identifying functional abnormalities and delivering tailored stimulation to improve neurological functioning and recovery.

Implementation Method 1

measuring an electroencephalography anomaly in a brain region

Methodology Applied
Scientific EffectElectroencephalography (EEG): Conduction (electrical)

Implementation Method 2

transcranial electrical stimulation to repair the neurological pathways

Methodology Applied
Scientific EffectTranscranial electrical stimulation: Conduction (electrical)

Data Source

PatentUS12427312B2Transcranial stimulation device and method based on electrophysiological testing
Publication Date: 2025.09.30 FIREFLY NEUROSCIENCE 2023 INC
  • US12427312B2 patent drawing
  • US12427312B2 patent drawing
  • US12427312B2 patent drawing

AI summary

The present method and system provides a neuromodulation therapy including receiving a plurality of input data relating to a patient, the input data including brain value measurements. The method and system includes analyzing the input data in reference to reference data generated based on machine learning operations associated with existing patient data and reference database data. Based thereon, the method and system includes electronically determining, a brain malady and a severity value for the patient and electronically generating a treatment protocol for the patient, the treatment protocol includes transcranial stimulation parameters. Therein, the method and system includes applying a transcranial stimulation using the transcranial stimulation parameters based on the treatment protocol.