Effervescent Tablet Supersaturated Calcium Phosphate Solution

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Solution Overview

Problem

Existing mouth rinses for inflammatory processes in the oral cavity require separate packaging and mixing of calcium and phosphate solutions, leading to increased manufacturing, transport, and storage costs, as well as inconvenience for patients, and often result in precipitation or opalescent solutions with insoluble particles.

Innovation Solution

An effervescent tablet that dissolves in water to provide a supersaturated solution of calcium and phosphate ions, maintaining clarity for at least 2 hours, eliminating the need for separate solutions and reducing packaging burdens.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If separate calcium and phosphate solutions are used, then the supersaturated solution can be prepared, but the manufacturing, transport, and storage costs increase due to separate packaging

Engineering Contradiction:
Improvesupersaturated solution preparationVSAvoidmanufacturing and storage cost
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The patent combines calcium and phosphate salts into a single effervescent tablet formulation, eliminating the need for separate packaging and mixing of calcium and phosphate solutions. This merging approach reduces manufacturing complexity, transport requirements, and storage costs while maintaining the ability to produce supersaturated solutions upon dissolution in water.

Inventive Principle:
Principle #5Merging (Combining)

2Reliability

If separate calcium and phosphate solutions are used, then the supersaturated solution can be prepared, but patient convenience decreases due to mixing requirements

Engineering Contradiction:
Improvesupersaturated solution preparationVSAvoidpatient convenience
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The patent merges calcium and phosphate components into a single ready-to-use effervescent tablet, eliminating the need for patients to mix separate solutions. The tablet is simply dissolved in water to produce the supersaturated solution, significantly improving patient convenience and ease of administration.

Inventive Principle:
Principle #5Merging (Combining)

3Reliability

If calcium and phosphate are mixed in solution, then the supersaturated solution is formed, but precipitation and opalescent solutions with insoluble particles occur

Engineering Contradiction:
Improvesupersaturated solution formationVSAvoidprecipitation and insoluble particles
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent utilizes effervescent reaction to change the pH parameter of the solution, creating an acidic environment that prevents premature precipitation of calcium phosphate. The effervescent tablet contains calcium salt, phosphate salt, and effervescing agents that generate CO2 and lower pH upon dissolution, keeping calcium and phosphate ions in solution until the desired supersaturated state is achieved.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The effervescent tablet offers a convenient, cost-effective, and patient-friendly solution that maintains a clear supersaturated calcium and phosphate mixture for extended use, avoiding precipitation and ensuring effective treatment of oral inflammatory processes.

Implementation Method 1

An effervescent tablet that dissolves in water to provide a supersaturated solution of calcium and phosphate ions

Methodology Applied
Scientific EffectEffervescence:

Implementation Method 2

maintaining clarity for at least 2 hours, eliminating the need for separate solutions

Methodology Applied
Scientific EffectSupersaturation: Supersaturation

Data Source

PatentUS11090259B2Effervescent tablet
Publication Date: 2021.08.17 RECORDATI UK LTD
  • US11090259B2 patent drawing

AI summary

The present invention relates to an effervescent tablet, which upon dissolution in water provides a solution useful as a mouth wash or oral rinse for the prevention or treatment of inflammatory processes of the soft tissues of the mouth, throat and oral cavity.