Effervescent Ruminant Bolus for Calcium and Yeast Delivery

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Solution Overview

Problem

Lactating cows face challenges with hypocalcemia and reduced dry matter intake post-calving, leading to increased risks of milk fever and poor lactational performance, as existing supplements fail to effectively address these issues.

Innovation Solution

A stable pressed solid bolus formulation containing calcium chloride, calcium carbonate, magnesium, potassium, and dried live active yeast, which reacts to release calcium and yeast in the reticulum, enhancing microbial action and feed intake.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If a solid bolus containing calcium chloride and acid-base ingredients is administered, then calcium delivery to the reticulum is improved, but the supplement does not address dry matter intake suppression

Engineering Contradiction:
Improvecalcium deliveryVSAvoidfunctional scope
Core Design Contradiction:
Quantity of substanceVSAdaptability or versatility

Solution Approach 1:

The bolus formulation combines multiple functions: calcium delivery through effervescent reaction, dry matter intake stimulation through dried active yeast, and electrolyte supplementation through magnesium and potassium. This multi-functional approach resolves the contradiction by addressing both calcium delivery and dry matter intake suppression within a single product.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The invention merges calcium chloride delivery mechanism with dried active yeast and electrolytes into a single compressed bolus. The effervescent reaction products (carbon dioxide gas and water) create conditions that facilitate the release and activation of yeast in the reticulum, combining multiple therapeutic actions in one dosage form.

Inventive Principle:
Principle #5Merging (Combining)

2Productivity

If dried active yeast is incorporated into the bolus formulation, then dry matter intake and microbial action are enhanced, but formulation stability becomes more difficult to achieve

Engineering Contradiction:
Improvedry matter intakeVSAvoidformulation stability
Core Design Contradiction:
ProductivityVSStability of the object's composition

Solution Approach 1:

The yeast is dried to reduce moisture content, transforming it from a fresh, unstable state to a stable, shelf-ready form. This parameter change (moisture reduction) allows the yeast to maintain viability while achieving formulation stability in the compressed bolus. The drying process preserves yeast activity while enabling long-term storage without refrigeration.

Inventive Principle:
Principle #35Parameter changes

3Ease of operation

If effervescent reaction components are included in the bolus, then calcium release into the reticulum is improved, but the complexity of the formulation increases

Engineering Contradiction:
Improvecalcium release efficiencyVSAvoidformulation complexity
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The bolus contains both acid and base components that automatically react with each other upon contact with rumen fluid, generating carbon dioxide gas and water. This self-service effervescent reaction requires no external activation or complex delivery mechanisms - the formulation itself provides the means for calcium release, simplifying the overall system while maintaining high efficiency.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The formulation effectively prevents hypocalcemia and increases dry matter feed intake and milk production, demonstrating direct economic benefits by providing a stable and efficient delivery of essential nutrients.

Implementation Method 1

The formulation also includes sufficient amounts of acidic and basic components which react to generate a gas release in an aqueous medium to accomplish effervescent release of calcium and dried active yeast into the reticulum via a solid bolus dosage form.

Methodology Applied
Scientific EffectEffervescent reaction: Chemical Bonding

Implementation Method 2

the yeast successfully enhances microbial action stimulating rumen fermentation

Methodology Applied
Scientific EffectFermentation: Fermentation

Data Source

PatentUS11523625B2Feed supplement bolus with active yeast
Publication Date: 2022.12.13 TECHMIX LLC

AI summary

A ruminant dietary supplement in the form of a pressed shelf-stable solid pill or bolus that effervesces when administered into the reticulum of a ruminant and releases calcium and dried active yeast.