Dirigent Gene EG261 Enhances Plant Pathogen Resistance
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Solution Overview
Problem
Current methods for enhancing pathogen resistance in plants, particularly against soybean cyst nematode, are limited in effectiveness and efficiency, and there is a need for more robust genetic solutions that can be integrated into plant breeding programs.
Innovation Solution
The use of EG261 nucleic acid sequences, including homologs, orthologs, paralogs, and fragments, to confer increased pathogen tolerance and resistance through genetic modification and breeding techniques, utilizing recombinant DNA constructs, vectors, and RNAi-based gene silencing to introduce these sequences into plant genomes.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional plant breeding methods are used to enhance pathogen resistance, then pathogen resistance can be improved, but the effectiveness and efficiency are limited
Solution Approach 1:
The patent changes the genetic parameters of plants by introducing specific dirigent gene sequences (EG261 and its orthologs/paralogs) to alter pathogen resistance characteristics. This molecular-level parameter change enables more effective and efficient pathogen resistance compared to conventional breeding, directly resolving the contradiction between reliability improvement and productivity limitation.
2Adaptability or versatility
If dirigent genes are used to confer pathogen resistance, then broad response to pathogens is achieved, but the complexity of genetic modification increases
Solution Approach 1:
The patent utilizes dirigent genes that provide universal, broad-spectrum pathogen resistance across multiple pathogen types (fungi, bacteria, insects, nematodes) and plant species. This multi-functional genetic element confers adaptability to various pathogens while maintaining relatively simple genetic modification approaches, resolving the contradiction between versatility improvement and complexity increase.
Data Source
AI summary
The present invention provides the identification and use of EG261, homologs of EG261, orthologs of EG261, paralogs of EG261, and fragments and variations thereof for altering, e.g. increasing, pathogen tolerance and/or resistance in plants.