Elastic Adapter Cone for Leak-Tight Capillary Automation

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Solution Overview

Problem

Manual replacement of capillaries in cell biology and medical applications is laborious, prone to errors, and limits automation due to lack of suitable fastening methods for leak-tight and precise connection to pump systems, especially in sterile environments where contamination risk is high.

Innovation Solution

An adapter assembly with a resilient adapter cone and a counter cone of different elasticity materials, allowing for high lateral force absorption and leak-tight sealing, enabling precise positioning and automated capillary exchange, using materials like polypropylene and V2A steel for the cones.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If glass capillaries are clamped by sealing rings, fittings or ferrules to connect to pump system, then connection is achieved, but leak-tightness is insufficient and automatic replacement is not suitable

Engineering Contradiction:
Improveleak-tightnessVSAvoidautomatic capillary replacement
Core Design Contradiction:
ReliabilityVSExtent of automation

Solution Approach 1:

The patent replaces traditional mechanical connection methods (sealing rings, fittings, ferrules) with a cone-based mechanical interference fit system. The adapter cone with conical outer surface engages with the counter cone's conical inner surface, creating a self-centering, leak-tight connection that can be automatically exchanged without manual intervention.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent changes the connection parameter from threaded or clamped interfaces to conical geometric interfaces with specific angle relationships. The conical outer surface of the adapter cone and conical inner surface of the counter cone create a deterministic mechanical engagement that ensures both leak-tightness and positional accuracy for automated operation.

Inventive Principle:
Principle #35Parameter changes

2Adaptability or versatility

If manual replacement of capillaries is performed, then capillary exchange is possible, but process is laborious and prone to errors

Engineering Contradiction:
Improvecapillary replacement capabilityVSAvoidreplacement time
Core Design Contradiction:
Adaptability or versatilityVSLoss of time

Solution Approach 1:

The conical interface design enables self-centering and self-alignment of the adapter cone within the counter cone, eliminating the need for manual positioning adjustments. The geometric constraint automatically ensures proper orientation and sealing, making the replacement process simple and error-proof for automated systems.

Inventive Principle:
Principle #25Self-service

3Manufacturing precision

If conventional fastening methods are used for capillaries, then connection is achieved, but position accuracy is insufficient for high precision work

Engineering Contradiction:
Improveconnection precisionVSAvoidfastening mechanism complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The patent employs conical surfaces (curved geometric forms) for both the adapter cone's outer surface and the counter cone's inner surface. This curved geometric interface provides self-centering action and distributes contact forces evenly, achieving high position accuracy and repeatable positioning without complex adjustment mechanisms.

Inventive Principle:
Principle #14Spheroidality (Curvature)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The adapter assembly ensures high leak-tightness and position accuracy, reducing the risk of contamination and increasing automation throughput by securely connecting capillaries to pump systems, even with small volumes and sensitive particles.

Implementation Method 1

the at least one section being made of a second material having a second elasticity greater than the first elasticity

Methodology Applied
Scientific EffectElasticity: Elasticity

Data Source

PatentUS11738335B2Adapter for receiving a capillary
Publication Date: 2023.08.29 ALS AUTOMATED LAB SOLUTIONS GMBH
  • US11738335B2 patent drawing
  • US11738335B2 patent drawing
  • US11738335B2 patent drawing

AI summary

An adapter assembly for receiving a capillary includes a passage, into which the capillary is or can be received. The adapter assembly has an adapter cone which is configured for being received in or on a correspondingly configured counter cone. The adapter cone, at least over a section for bringing the adapter cone into contact with the counter cone, includes an elastic material that is more elastic than the material of the counter cone. The invention further relates to a counterpart for connecting to the adapter, to an apparatus and to a method for automatically exchanging capillaries.