Elastic Cover Sheet Valve for Liquid Storage and Release
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Solution Overview
Problem
Conventional methods for liquid storage and release in biochemical reactions involve complex structures, high costs, large dimensions, and poor reliability, particularly in point-of-care testing where ampoules and bladders require mechanical or external forces for liquid release, leading to issues with chip size, safety, and operational complexity.
Innovation Solution
A liquid storage and release chip with a structural layer and elastic cover sheet, featuring a valve opening and centrifugal positioning hole, allows for sealed storage and easy release of liquids through a valve column and centrifugal operation, simplifying the structure and operation while reducing size and cost.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If ampoules are used for liquid storage, then storage stability is improved, but device complexity and processing difficulty increase
Solution Approach 1:
The invention extracts the liquid storage function from the complex ampoule structure and integrates it directly into the chip's reaction cavity. The storage cavity is formed as an integral part of the chip structure, eliminating the need for separate ampoules and their complex breaking mechanisms.
Solution Approach 2:
The invention merges the liquid storage function with the reaction device by forming a storage cavity within the chip structure itself. The storage cavity and reaction cavity are integrated into a single chip component, eliminating the need for separate ampoules and reducing overall device complexity.
2Reliability
If ampoules are used for liquid storage, then storage stability is improved, but chip dimension increases
Solution Approach 1:
The invention merges the liquid storage function with the reaction device by forming a storage cavity within the chip structure. The storage cavity and reaction cavity are integrated into a single chip component, eliminating the need for separate ampoules and reducing overall device complexity.
Solution Approach 2:
The storage cavity is nested within the chip structure, with the partition wall separating it from the reaction cavity. This nested arrangement allows efficient use of space within the chip, minimizing the overall chip dimension while maintaining both storage and reaction functions.
3Object-affected harmful factors
If bladders are used for liquid storage, then safety is improved (no broken glass), but device complexity increases
Solution Approach 1:
The invention extracts the liquid storage function from the bladder structure and integrates it directly into the chip's reaction cavity. The storage cavity is formed as an integral part of the chip structure, eliminating the need for separate bladders and their complex puncturing mechanisms.
Solution Approach 2:
The invention merges the liquid storage function with the reaction device by forming a storage cavity within the chip structure itself. The storage cavity and reaction cavity are integrated into a single chip component, eliminating the need for separate bladders and reducing overall device complexity.
4Ease of operation
If laser irradiation is used for liquid release, then motion mechanism is eliminated, but manufacturing complexity and cost increase
Solution Approach 1:
The invention performs preliminary action by pre-forming the partition wall with a through-hole during chip manufacturing. This eliminates the need for post-manufacturing laser drilling or other complex release mechanisms, as the liquid release path is already prepared in advance.
Solution Approach 2:
The invention replaces complex laser irradiation mechanisms with a simple mechanical valve column that can be inserted through the pre-formed hole. This substitution simplifies both the manufacturing process and the operational mechanism while maintaining ease of liquid release.
5Device complexity
If centrifugal force is used for liquid release, then motion mechanism is simplified, but liquid may be damaged by high temperature
Solution Approach 1:
The invention performs preliminary action by pre-forming the partition wall with a through-hole during chip manufacturing. This eliminates the need for post-manufacturing laser drilling or other complex release mechanisms, as the liquid release path is already prepared in advance.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The solution enables reliable, cost-effective, and compact liquid storage and release, avoiding the need for complex mechanisms and minimizing adverse effects on the liquid, facilitating integration and portable operation.
Implementation Method 1
the valve column is configured to push up a portion, covering the valve opening, of the elastic cover sheet
Implementation Method 2
a liquid storage and release chip... allows for sealed storage and easy release of liquids through a valve column and centrifugal operation
Data Source
AI summary
A liquid storage and release chip provided according to the present application includes a structural layer and an elastic cover sheet. An end surface of one side of the structural layer is provided with a liquid storage cell and a liquid quantitation cell, the liquid storage cell and the liquid quantitation cell are separated by a common partition wall, and the partition wall is provided with a valve opening passing through end surfaces of two sides of the structural layer. The elastic cover sheet is attached to the structural layer and covers the liquid storage cell, the liquid quantitation cell and the valve opening in a sealed manner, and the valve opening allows a spool to be inserted in the valve opening in a sealed manner to push up a portion, covering the valve opening, of the elastic cover sheet.