Elastic Fluidic Coupling for High-Pressure HPLC Sealing

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Solution Overview

Problem

Existing fluidic couplings in high-performance liquid chromatography (HPLC) systems face challenges in providing reliable and repeatable sealing under high pressures, leading to issues such as internal and external band broadening, which compromises the resolution and identification of sample compounds.

Innovation Solution

A fluidic coupling mechanism using a sealing element between two elastic structures that deform elastically to establish fluid communication while maintaining a seal, allowing for repeatable coupling and decoupling, even under pressures up to 2000 bar, utilizing materials like metal and polymers for the structures and sealing element.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If a sealing element is used to fluidically couple two structures under high pressure, then reliable sealing is improved, but deformation of the sealing element increases

Engineering Contradiction:
Improvesealing reliabilityVSAvoidsealing element deformation
Core Design Contradiction:
ReliabilityVSShape

Solution Approach 1:

The patent introduces an elastic structure that changes its physical state (from rigid to elastic) to adapt to pressure conditions. The elastic structure deforms under pressure to maintain contact with the sealing element, ensuring continuous sealing while accommodating the deformation through controlled elastic behavior rather than permanent deformation.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The fluidic coupling combines multiple materials with different properties: a sealing element (typically elastomeric), an elastic structure (with specific elastic modulus), and rigid fluidic structures. This composite approach allows each material to perform its optimal function - the sealing element provides sealing, the elastic structure provides pressure compensation, and the rigid structures provide structural integrity.

Inventive Principle:
Principle #40Composite materials

2Reliability

If pressure between fluidic structures is increased to improve sealing, then sealing reliability is improved, but deformation of structures increases

Engineering Contradiction:
Improvefluidic coupling reliabilityVSAvoidstructure deformation
Core Design Contradiction:
ReliabilityVSShape

Solution Approach 1:

The elastic structure's key property (elastic modulus) is selected to match the operating pressure range. At low pressures, the structure remains relatively rigid for precise alignment. At high pressures, it becomes sufficiently compliant to deform and maintain sealing contact, thus adapting its mechanical properties to the operating conditions.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The elastic structure acts as a cushioning element that anticipates and absorbs pressure-induced deformations. By being pre-configured with appropriate elastic properties, it prevents excessive force transmission to the rigid fluidic structures, thereby protecting them from deformation while maintaining sealing under pressure.

Inventive Principle:
Principle #11Beforehand cushioning (Prior cushioning)

3Stability of the object's composition

If rigid structures are used for fluidic coupling, then structural stability is improved, but sealing reliability under pressure deteriorates

Engineering Contradiction:
Improvestructural stabilityVSAvoidsealing reliability
Core Design Contradiction:
Stability of the object's compositionVSReliability

Solution Approach 1:

The coupling mechanism uses different structural qualities in different locations: rigid fluidic structures for structural stability and fluid transmission, but an elastic structure locally at the sealing interface to accommodate pressure-induced deformations. This local adaptation of material properties resolves the contradiction between overall rigidity and local compliance.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The elastic structure serves as an intermediary element between the rigid fluidic structures and the sealing element. It mediates the interaction by absorbing mechanical stresses and maintaining optimal contact pressure, thus protecting the rigid structures from deformation while ensuring reliable sealing.

Inventive Principle:
Principle #24Intermediary (Mediator)

4Reliability

If sealing element deformation is allowed to improve sealing, then sealing reliability is improved, but fluidic coupling precision deteriorates

Engineering Contradiction:
Improvesealing reliabilityVSAvoidcoupling precision
Core Design Contradiction:
ReliabilityVSManufacturing precision

Solution Approach 1:

The elastic structure's deformation characteristics are carefully selected to change only after a certain pressure threshold is reached. At low pressures (during coupling), the structure remains rigid for precise alignment. Above the threshold, it becomes compliant to allow sealing deformation, thus separating the coupling phase from the sealing phase in terms of mechanical behavior.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The elastic structure is pre-configured with specific geometric and material properties that enable it to maintain a predetermined shape during the coupling phase, ensuring precise alignment. Only after coupling is established does it begin to deform under pressure to maintain sealing, thus performing different functions at different stages.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution ensures reliable fluidic communication and sealing, reducing deformation and maintaining peak sharpness, thereby enhancing the resolution and identification of sample compounds in HPLC systems.

Implementation Method 1

the first elastic structure is elastically deformed by the sealing element

Methodology Applied
Scientific EffectElastic deformation: Elasticity

Data Source

PatentUS12569781B2Fluidically coupling with elastic structure deformable by sealing element
Publication Date: 2026.03.10 AGILENT TECHNOLOGIES INC
  • US12569781B2 patent drawing
  • US12569781B2 patent drawing
  • US12569781B2 patent drawing

AI summary

A fluidic coupling is positioned between a first fluidic structure and a second fluidic structure. The first fluidic structure has a first channel configured for conducting fluid and opening at a first opening at a first surface of the first fluidic structure. The second fluidic structure has a second channel configured for conducting fluid and opening at a second opening at a second surface of the second fluidic structure. The fluidic coupling includes a sealing element and an elastic structure. The elastic structure may be elastically deformed by the sealing element, thus allowing a fluidic communication between the first channel and the second channel.