Elastomeric Construct Dynamic Strain Profile Determination

The patent creates a physical model that copies the essential mechanical properties and geometry of the human heart, allowing strain profile measurements to be performed on the model rather than requiring complex in vivo testing. This model replicates the deformation characteristics of actual cardiac tissue under various loading conditions.

The physical model serves as an intermediary between the elastomeric construct and actual human tissue. It allows the construct to be tested in a controlled environment that mimics in vivo conditions without requiring direct implantation or complex in vivo measurement systems.

The physical model replicates the mechanical response of cardiac tissue without using actual biological tissue. This allows researchers to gather comprehensive data on tissue-construct interactions, strain distribution, and force transfer characteristics while completely avoiding tissue trauma and ethical concerns associated with animal or human testing.

The patent converts the limitation of not having real tissue into a benefit by creating a controlled physical model that eliminates tissue trauma while still providing sufficient mechanical data for construct development and optimization.

The patent applies preliminary action by thoroughly testing and optimizing the elastomeric construct's strain profile on physical models before actual implantation. This allows the construct to be pre-adjusted to match the specific mechanical characteristics of the patient's heart, ensuring optimal support while minimizing the risk of tissue trauma during and after implantation.

The patent utilizes parameter changes by adjusting the elastomeric material properties, construct geometry, and inflation pressures based on data obtained from physical model testing. These parameters are optimized to provide the necessary mechanical support for heart pump function while keeping stresses on the tissue within safe limits.