Electro-osmotic Pump Bubble-Free Operation

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Solution Overview

Problem

There is a need for inexpensive, reliable electro-osmotic pumps that can deliver fluids, such as drugs or allergens, to a subject without fouling and at desired intervals or rates, as existing pumps often suffer from issues like gas bubble interference and high operational costs.

Innovation Solution

A direct current electro-osmotic pump system is developed, featuring a porous cathode and anode without platinum, along with a porous ceramic membrane, operating at a potential difference of up to 3 volts without producing visible bubbles, using Ag2O and Ag electrodes, and a silica-based membrane with specific dimensions and coatings to ensure efficient and bubble-free fluid delivery.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If platinum electrodes are used in electro-osmotic pumps, then the pump reliability is improved, but the manufacturing cost increases

Engineering Contradiction:
Improvepump reliabilityVSAvoidmanufacturing cost
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The patent replaces expensive platinum electrodes with cheaper alternative materials such as carbon, silver, or stainless steel electrodes. These electrodes are designed to be consumable or replaceable, accepting that they may degrade over time but providing cost-effective operation for the intended application lifecycle. This substitution directly addresses the contradiction by dramatically reducing manufacturing cost while maintaining adequate reliability for the specific drug delivery application.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Solution Approach 2:

The patent modifies the operating parameters by using low voltage (below 3 volts) DC electro-osmosis to minimize electrolysis and gas bubble formation. This parameter change allows the use of less expensive electrode materials that would otherwise be unsuitable at higher voltages, thereby reducing manufacturing cost while maintaining pump reliability through optimized operating conditions.

Inventive Principle:
Principle #35Parameter changes

2Productivity

If high voltage is applied to drive fluid flow, then the productivity is improved, but gas bubble formation increases

Engineering Contradiction:
Improvefluid flow rateVSAvoidgas bubble formation
Core Design Contradiction:
ProductivityVSObject-generated harmful factors

Solution Approach 1:

The patent fundamentally changes the operating voltage parameter from conventional high voltage to low voltage (below 3 volts) DC operation. This parameter change reduces electrolysis and gas bubble formation while maintaining adequate fluid flow rates through the electro-osmotic effect in the porous membrane, directly resolving the contradiction between productivity and harmful gas generation.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent employs porous ceramic membranes with specific pore structures that enhance electro-osmotic flow efficiency. The porous material allows effective fluid pumping at low voltages by utilizing the electro-osmotic effect within the pore structure, thereby achieving adequate productivity without the gas bubble formation associated with high voltage operation.

Inventive Principle:
Principle #31Porous materials

3Device complexity

If simple electrode structures are used, then the device complexity is reduced, but the pump reliability deteriorates

Engineering Contradiction:
Improveelectrode structure complexityVSAvoidpump operation stability
Core Design Contradiction:
Device complexityVSReliability

Solution Approach 1:

The patent uses simple, inexpensive electrode materials such as carbon rods, silver wires, or stainless steel elements with basic geometries. These simple structures are accepted as consumable components that may degrade over time, providing adequate reliability for the intended application duration while minimizing device complexity and manufacturing cost.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Solution Approach 2:

The patent compensates for the simplicity of electrode structures by optimizing operating parameters, specifically using low voltage DC operation and controlling current density. This parameter optimization ensures stable pump operation and reliable fluid delivery despite the use of simple electrode geometries, resolving the contradiction between device complexity and pump reliability.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system provides a low-cost, reliable method for delivering fluids, ensuring consistent flow rates and preventing bubble formation, making it suitable for drug delivery systems without the need for expensive platinum components.

Implementation Method 1

a direct current electro-osmotic pump comprising: a porous cathode free of platinum; a porous anode free of platinum; and a porous ceramic membrane between the cathode and the anode

Methodology Applied
Scientific EffectElectro-osmosis: Electro-Osmosis

Data Source

PatentEP2848271B1Electro-osmotic pumps
Publication Date: 2016.04.27 BOARD OF RGT THE UNIV OF TEXAS SYST
  • EP2848271B1 patent drawingFigure 1~2
  • EP2848271B1 patent drawingFigure 3A~3B
  • EP2848271B1 patent drawingFigure 4A~4D

AI summary

A direct current electro-osmotic pump comprising: a porous, platinum-free cathode; a porous, platinum-free anode; and a porous ceramic membrane between the cathode and the anode, wherein at least a part of the surface of the membrane is in physical contact with the anode, and at least a part of the opposite side of the membrane is in physical contact with the cathode, and wherein the pump is configured to operate at a potential difference (V) between the anode and the cathode of V≦3 volts without producing bubbles visible to the naked eye.