Electrochemical Adipose Tissue Treatment via pH Control

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Solution Overview

Problem

Current methods for treating adipose tissue, such as liposuction and pharmacologic treatments, are invasive, costly, or have limitations in precision and safety, and there is a need for improved techniques to effectively shape and remove subcutaneous fat without significant tissue damage.

Innovation Solution

The method involves creating an electrochemical reaction in adipose tissue using an electrolytic solution and needle electrodes connected to a potentiostat, which applies a controlled electrical potential to generate specific chemical reactions that break down fat molecules, allowing for localized and minimally invasive fat removal and shaping.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Loss of substance

If liposuction or pharmacologic treatments are used to remove fat, then fat removal is achieved, but tissue damage and invasiveness increase

Engineering Contradiction:
Improvefat removalVSAvoidtissue damage
Core Design Contradiction:
Loss of substanceVSObject-affected harmful factors

Solution Approach 1:

The patent changes the chemical parameters of the tissue environment by controlling pH levels. Acidic pH (pH 2-4) is used to dissolve fat molecules through chemical breakdown, while basic pH (pH 10-12) is used to neutralize and emulsify the dissolved fat. This parameter-based approach allows selective fat removal without mechanical trauma to surrounding tissues.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent replaces mechanical fat removal methods (suction, cutting, freezing) with electrochemical reactions. Electrical potential applied through electrodes generates local pH changes that chemically dissolve fat molecules, substituting mechanical force with chemical transformation to achieve fat removal with minimal tissue damage.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Productivity

If surgical procedures like liposuction are performed, then fat removal is effective, but procedure complexity and cost increase

Engineering Contradiction:
Improvefat removal efficiencyVSAvoidprocedure complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent employs the body's own physiological processes to remove fat. The electrochemical reactions dissolve fat into soluble molecules that are naturally absorbed and metabolized by the body's lymphatic and circulatory systems. This self-service mechanism eliminates the need for complex surgical infrastructure, specialized surgical teams, and expensive surgical facilities.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent extracts only the fat molecules from the tissue through selective electrochemical dissolution, leaving the surrounding tissue intact. This extraction approach removes the need for complex surgical techniques required to protect and preserve surrounding structures during mechanical fat removal.

Inventive Principle:
Principle #2Taking out (Extraction)

3Loss of substance

If thermal energy methods (laser, RF, ultrasound) are used to treat fat, then fat destruction is achieved, but risk of thermal damage to surrounding tissue increases

Engineering Contradiction:
Improvefat destructionVSAvoidthermal damage
Core Design Contradiction:
Loss of substanceVSObject-affected harmful factors

Solution Approach 1:

The patent substitutes thermal energy with electrical energy to achieve fat destruction. Electrical potential applied through electrodes creates localized electrochemical reactions that dissolve fat through pH changes rather than heat generation. This substitution eliminates the thermal diffusion problem that causes damage to surrounding tissues in laser, RF, and ultrasound methods.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent creates highly localized chemical environments at the electrode-tissue interface where extreme pH values (2-4 for acid, 10-12 for base) are confined to microscopic regions immediately surrounding the electrodes. This local quality approach allows intense fat dissolution at the treatment site without propagating harmful effects to surrounding tissues, unlike thermal methods where heat diffuses through tissue.

Inventive Principle:
Principle #3Local quality

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach allows for precise, low-cost, and safe reshaping of adipose tissue with reduced tissue damage, as it utilizes electrochemical reactions to break down fat cells and molecules, enabling effective fat reduction and contouring without the need for extensive surgery or general anesthesia.

Implementation Method 1

creating an electrochemical reaction in the tissue; wherein the electrochemical reaction occurs in the presence of an electrolytic solution in the tissue

Methodology Applied
Scientific EffectElectrochemical reaction: Electrolysis

Implementation Method 2

electrochemical reaction occurs in the presence of an electrolytic solution in the tissue

Methodology Applied
Scientific EffectElectrolysis: Electrolysis

Implementation Method 3

electrochemically generating acid and base molecules to break down fat molecules

Methodology Applied
Scientific EffectHydrolysis: Hydrolysis

Data Source

PatentUS11071578B2Method and apparatus to electrochemically treat adipose tissue in the human body
Publication Date: 2021.07.27 RGT UNIV OF CALIFORNIA
  • US11071578B2 patent drawing
  • US11071578B2 patent drawing
  • US11071578B2 patent drawing

AI summary

A method of altering adipose tissue includes creating an electrochemical reaction in the tissue, wherein the electrochemical reaction occurs in the presence of an electrolytic solution in the tissue.