Electrolysis-Based Liquid Phase Transfer for Acid Extraction

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Solution Overview

Problem

Existing extraction processes for target substances, such as carboxylic acids produced by fermentation, are uneconomical due to the need for pH adjustment using acids or bases, leading to salt separation and disposal issues, as well as complex recovery of acids or bases, and limited operational efficiency in downstream processes.

Innovation Solution

A method involving electrolysis in electrode chambers to create pH changes in an aqueous phase, allowing for the transfer of target substances between liquid phases without the need for external pH adjustment, thereby avoiding salt formation and simplifying the process by using electrical means to alter protonation states and solubility, facilitating efficient extraction and concentration.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If acids or bases are added to adjust pH values for extraction, then the target substance can be transferred between phases, but significant amounts of salt are generated that must be separated and disposed of

Engineering Contradiction:
Improveextraction efficiencyVSAvoidsalt disposal
Core Design Contradiction:
ProductivityVSLoss of substance

Solution Approach 1:

The patent replaces the chemical system (adding acids or bases for pH adjustment) with an electrochemical system (electrolysis to generate H+ or OH- ions). This substitution eliminates the need for external acid/base addition and the subsequent salt formation problem, as the pH adjustment is achieved through in-situ electrolysis rather than chemical reagent addition

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent changes the method of pH control from chemical reagent addition to electrochemical parameter control. By adjusting electrolysis conditions (current, voltage, time), the pH is dynamically controlled without introducing external salts, thus resolving the contradiction between extraction efficiency and salt disposal requirements

Inventive Principle:
Principle #35Parameter changes

2Productivity

If acids or bases are used for pH adjustment, then extraction can proceed, but the recovery of acids or bases used is complex

Engineering Contradiction:
Improveextraction rateVSAvoidrecovery process complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent replaces the complex chemical recovery process with a simpler electrochemical regeneration process. The electrolyte is regenerated in-situ through electrolysis, which decomposes the salt back into H+ or OH- ions and the corresponding gas (H2 or O2), eliminating the need for complex separation and recovery equipment

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The electrolyte serves a dual function: it enables pH adjustment during extraction and automatically regenerates itself through electrolysis. This self-service capability eliminates the need for external recovery systems, reducing device complexity while maintaining high extraction rates

Inventive Principle:
Principle #25Self-service

3Reliability

If downstream processes for salt separation are used, then salt can be removed, but these processes can only be operated economically up to a maximum salt content

Engineering Contradiction:
Improvepurification qualityVSAvoidoperational efficiency
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The patent replaces downstream salt separation processes with in-situ electrolysis-based pH adjustment. By generating H+ or OH- ions directly in the extraction phase through electrolysis, the method avoids salt formation entirely, eliminating the need for nanofiltration, reverse osmosis, or other salt separation technologies

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This method enables efficient transfer and concentration of target substances between phases, reducing economic and environmental burdens associated with salt disposal and acid/base recovery, while allowing for selective separation and purification of acids based on pH adjustments, enhancing process efficiency and reducing operational costs.

Implementation Method 1

a pH change is generated in the aqueous phase by the H and/or OH ions produced during the electrolysis

Methodology Applied
Scientific EffectElectrolysis: Electrolysis

Data Source

PatentEP3746582B1Method for transferring a target substance between two liquid phases
Publication Date: 2024.05.22 RWTH AACHEN UNIV
  • EP3746582B1 patent drawingFigure 1
  • EP3746582B1 patent drawingFigure 2
  • EP3746582B1 patent drawingFigure 3A~3C

AI summary

The invention relates to a method for transferring a target substance (5), particularly a target molecule (5), between two liquid phases (4, 6; 6, 8; 6, 11), of which at least one phase (4, 6) comprises the target substance (5) to be transferred and at least one phase (4, 8, 11) is an aqueous phase, where at least the aqueous phase (4, 8, 11) is arranged in one of two electrode chambers (1a, 1b, 10a, 10b) which are electroconductively connected, preferably by charge carrier exchange, and separated in terms of the volumes thereof, preferably where the phases (4, 6; 6, 8; 6,11) are arranged together in one of two electrode chambers (1a, 1b, 10a, 10b) which are electroconductively connected and separated in terms of the volumes thereof, and a pH-value modification is generated by the H and/or OH ions created during the electrolysis in the aqueous phase (4, 8, 11), said modification initiating a transfer process of the target substance (5) between the phases (4, 6; 6, 8; 6,11). The invention also relates to the use of the method for enrichment and subsequent isolation of the target substance (5).