Electron Linear Accelerator for Molybdenum-99 Production

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

The global supply of molybdenum-99 (99Mo) is uncertain due to the aging of nuclear reactors used for its production, leading to shortages and unreliable medical diagnostic capabilities, as current methods for producing 99Mo from molybdenum-100 (100Mo) are inefficient and prone to producing unwanted isotopes.

Innovation Solution

The use of high-power electron linear accelerators to irradiate 100Mo targets with bremsstrahlung photons, generating 99Mo through photo-neutron reactions, while employing separate cooling systems and buffers to mitigate radiolysis and corrosion effects, thereby increasing yield and reducing the production of undesirable isotopes.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If nuclear reactors are used to produce 99Mo from 235U fission, then large-scale production is achieved, but supply reliability deteriorates due to reactor aging and shutdowns

Engineering Contradiction:
Improveproduction scaleVSAvoidsupply reliability
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent changes the production method from nuclear fission to photo-neutron reaction using electron linear accelerators. This parameter change in the production mechanism eliminates dependence on aging nuclear reactors, thereby maintaining large-scale production capability while significantly improving supply reliability through a more stable and controllable production process

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent replaces the nuclear reactor system with an electron linear accelerator system. This substitution transitions from a mechanical/nuclear system prone to aging and shutdowns to a particle accelerator system that offers greater operational stability and reliability, while maintaining the capability for large-scale 99Mo production

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Ease of manufacture

If conventional methods are used to produce 99Mo from 100Mo, then production is achieved, but manufacturing precision deteriorates due to unwanted isotope production

Engineering Contradiction:
Improveproduction feasibilityVSAvoidisotope purity
Core Design Contradiction:
Ease of manufactureVSManufacturing precision

Solution Approach 1:

The patent applies local quality by using electron beams with specific energy parameters (10-30 MeV) tailored to the 100Mo photo-neutron reaction cross-section. This localized optimization of beam energy ensures maximum production of the desired 99Mo isotope while minimizing the formation of unwanted isotopes, thereby improving manufacturing precision without compromising production feasibility

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent employs periodic action through pulsed electron beam irradiation and controlled target rotation. This periodic delivery of radiation allows for precise control of the nuclear reaction process, enhancing isotope purity by optimizing the interaction time and energy distribution while maintaining efficient production rates

Inventive Principle:
Principle #19Periodic action

3Productivity

If high-power electron beams are used to irradiate 100Mo targets, then 99Mo yield increases, but harmful factors worsen due to radiolysis and corrosion

Engineering Contradiction:
Improve99Mo yieldVSAvoidradiolysis and corrosion
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The patent introduces an intermediary cooling system with radiolysis buffers between the high-power electron beam and the 100Mo target. This intermediary layer absorbs the harmful radiolysis effects and prevents direct corrosion of the target, allowing high-power beam irradiation to continue at full intensity to maintain high 99Mo yield while protecting the target integrity

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent converts the harmful radiolysis effect into a beneficial protective layer. By allowing controlled radiolysis to occur and forming a protective oxide layer on the target surface, the harmful radiation effect is transformed into a protective mechanism that actually reduces further corrosion and target degradation, enabling sustained high-power irradiation for maximum 99Mo production

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This method provides a reliable and efficient production of 99Mo with reduced risks of producing other isotopes, enhancing the stability of the global supply and ensuring consistent medical diagnostic capabilities.

Implementation Method 1

high-power electron linear accelerators to irradiate 100Mo targets with bremsstrahlung photons

Methodology Applied
Scientific EffectBremsstrahlung radiation:

Implementation Method 2

generating 99Mo through photo-neutron reactions

Methodology Applied
Scientific EffectPhoto-neutron reaction:

Implementation Method 3

employing separate cooling systems and buffers to mitigate radiolysis and corrosion effects

Methodology Applied
Scientific EffectThermal conduction: Conduction (thermal)

Data Source

PatentUS9837176B2Production of molybdenum-99 using electron beams
Publication Date: 2017.12.05 CANADIAN LIGHT SOURCE INC
  • US9837176B2 patent drawing
  • US9837176B2 patent drawing
  • US9837176B2 patent drawing

AI summary

An apparatus for producing 99Mo from a plurality of 100Mo targets through a photo-nuclear reaction on the 100Mo targets. The apparatus comprises: (i) an electron linear accelerator component; (ii) an energy converter component capable of receiving the electron beam and producing therefrom a shower of bremsstrahlung photons; (iii) a target irradiation component for receiving the shower of bremsstrahlung photons for irradiation of a target holder mounted and positioned therein. The target holder houses a plurality of 100Mo target discs. The apparatus additionally comprises (iv) a target holder transfer and recovery component for receiving, manipulating and conveying the target holder by remote control; (v) a first cooling system sealingly engaged with the energy converter component for circulation of a coolant fluid therethrough; and (vi) a second cooling system sealingly engaged with the target irradiation component for circulation of a coolant fluid therethrough.