Electronic Detection Device for Test Strip Accuracy
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Conventional electronic analyzers for test strips may produce inaccurate results due to unstable factors like light intensity and colloidal gold mobility during the chromatographic process, as they typically perform a single analysis before outputting results, which can lead to errors if the reaction has not fully stabilized.
Innovation Solution
The method involves detecting signals in both the detection and reference zones before and after adding a sample, calculating judgement values based on previous signals, and determining results multiple times to ensure accuracy, accounting for potential instability during the reaction process.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If a single analysis is performed before outputting results, then the productivity is improved, but the measurement precision deteriorates due to unstable reaction conditions
Solution Approach 1:
The patent implements periodic detection at multiple time points during the reaction process. Instead of a single analysis, the system performs repeated measurements at predetermined intervals, allowing the reaction to stabilize while maintaining efficient throughput through automated periodic sampling and processing.
Solution Approach 2:
The system performs preliminary detections before the reaction is complete to monitor the development of the reaction. By conducting multiple preliminary measurements during the reaction process, the system can determine when stabilization occurs and only then finalize the result, ensuring accuracy without unnecessary delays.
2Loss of time
If detection is performed before reaction stabilization, then the testing time is reduced, but the reliability deteriorates due to mobile colloidal gold and unstable factors
Solution Approach 1:
The system uses feedback from multiple detection readings to monitor reaction stability. By continuously sampling the reaction zones and comparing results across time points, the system can detect when the reaction has stabilized and when colloidal gold mobility has ceased, ensuring reliable results are only reported after stabilization is confirmed.
Solution Approach 2:
The detection system dynamically adjusts its operation based on reaction progress. It performs frequent initial detections to track the mobile colloidal gold, then reduces detection frequency once stabilization is detected, optimizing both speed and reliability by adapting to the changing reaction state.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach improves the accuracy of electronic analytical determination by performing multiple analyses after the sample is added, reducing the likelihood of errors caused by unstable reaction conditions.
Implementation Method 1
The only one detector disposed between the two light sources and detects light reflected from the test zone and the control zone alternately
Implementation Method 2
Conventional electronic analyzer for analyzing analyte, such as an electronic pregnancy test, usually involves inserting a test strip, such as a colloidal-gold-labeled immunochromatographic test strip
Data Source
Figure 1
Figure 2
Figure 3
AI summary
Method and apparatus for electronic detection and determination is disclosed herein, comprising the following steps: detecting a signal T0 in a detection zone and a signal R0 in a reference zone before a sample is added; adding a sample and detecting the signals in each of the detection zone and the reference zone at an interval of a second preset period; calculating a judgement value based on 2k immediately previous signals in each of the detection zone and the reference zone, the signal T0 in the detection zone before the sample is added, and the signal R0 in the reference zone before the sample is added, each time when k successive signals are detected in each of the detection zone and the reference zone; and determining a judgement result based on m successive judgement values and a preset result threshold corresponding to a current detection time. The present disclosure takes into account potential unstable factors during the reaction process of a test strip and provides a determination result after performing determination for multiple times, ensuring the accuracy of the results and improving the accuracy of electronic analytical determination.