82Sr/82Rb Elution System with External Dose Calibrator
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Solution Overview
Problem
Existing 82Sr/82Rb elution systems often have the dose calibrator integrated within the main cabinet structure, which can expose users and patients to high radioactivity and lacks flexibility in maintaining precision radioactivity detection, and there is a need for safer configurations with the dose calibrator positioned outside the main cabinet structure.
Innovation Solution
The 82Sr/82Rb elution system is designed with the dose calibrator on a separate mobile platform, allowing for remote placement and secure access, with shielding materials like depleted uranium, lead, or bismuth to prevent radioactivity exposure, and a controller to manage the pump and valves for delivering a constant activity rate of rubidium solution to patients.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Volume of moving object
If the dose calibrator is integrated within the main cabinet structure, then the system structure is compact, but user and patient exposure to high radioactivity increases
Solution Approach 1:
The system is divided into two separate modules: a mobile platform containing the generator and elution system, and a stationary dose calibrator. This segmentation allows the dose calibrator to be positioned away from the high radioactivity generation area while maintaining system functionality.
Solution Approach 2:
The dose calibrator is extracted from the main cabinet structure and positioned on a separate stationary platform. This extraction removes the dose calibrator from the high radioactivity environment, protecting users and patients from excessive exposure while preserving the calibrator's measurement function.
2Stability of the object's composition
If the dose calibrator is integrated within the main cabinet structure, then the system is stable, but flexibility in maintaining precision radioactivity detection is reduced
Solution Approach 1:
By segmenting the system into mobile and stationary components, the dose calibrator can be positioned optimally for precise measurements without being constrained by the mobile platform's limitations, thus maintaining measurement precision while the mobile platform provides operational flexibility.
Solution Approach 2:
A removable attachment mechanism serves as an intermediary between the mobile platform and the stationary dose calibrator, enabling flexible connection and disconnection. This intermediary allows the system to adapt between mobile and stationary configurations, maintaining both stability during use and flexibility for repositioning.
3Object-affected harmful factors
If the dose calibrator is positioned outside the main cabinet structure, then user and patient safety is improved, but system complexity increases
Solution Approach 1:
The system is segmented into two independently functional modules that can operate separately. The mobile platform handles generation and elution, while the stationary dose calibrator handles measurement. This segmentation simplifies the overall system design by allowing each module to be optimized independently rather than requiring a complex integrated design.
Solution Approach 2:
The removable attachment mechanism provides multi-functionality, allowing the system to operate in multiple configurations: connected mode for integrated operation, disconnected mode for separate operation, and repositionable modes. This universality reduces complexity by using a single mechanism to enable multiple operational scenarios.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This configuration ensures user and patient safety by isolating the dose calibrator from high radioactivity fields and maintaining precise radioactivity detection, while allowing for flexible mobility and precise control of the rubidium solution delivery, adhering to stringent safety limits and quality control standards.
Implementation Method 1
shielding materials like depleted uranium, lead, or bismuth to prevent radioactivity exposure
Implementation Method 2
a controller to manage the pump and valves for delivering a constant activity rate of rubidium solution to patients
Data Source
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Figure 5~6A
AI summary
Disclosed herein are rubidium elution systems comprising a primary assembly including a 82Sr/82Rb generator, an activity detector, a waste container, a pump system, a sensor, a tubing circuit, at least one valve, and a computer; and a dose calibrator outside the primary assembly. The system may have an interface for configuring the dose calibrator, and a locking means for preventing access to the interface and reconfigurations of its parameters. Moreover, the dose calibrator may be in electronic communication with the computer of the system. Furthermore, the electronic communication can be embodied with an electronic cable having a breakaway connector. Also, the dose calibrator may be positioned on a mobile platform.