Emamectin Benzoate Aqueous Formulation Without Organic Solvents

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Solution Overview

Problem

Current pesticidal formulations of emamectin benzoate rely on organic solvents, which are environmentally harmful and lead to instability, high production costs, and short shelf life, limiting their effectiveness and environmental friendliness.

Innovation Solution

A novel aqueous solution formulation of emamectin benzoate using anionic surfactants and natural high molecular surfactants, eliminating organic solvents and incorporating antifreezing, defoaming, and light stabilizing agents to enhance stability, efficacy, and environmental sustainability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If organic solvents are used to dissolve emamectin benzoate, then solubility and formulation stability are improved, but environmental friendliness deteriorates and health hazards increase

Engineering Contradiction:
Improveformulation stabilityVSAvoidenvironmental friendliness
Core Design Contradiction:
Stability of the object's compositionVSObject-affected harmful factors

Solution Approach 1:

The patent extracts and removes organic solvents from the pesticidal formulation system, replacing them with water as the sole solvent. This extraction of the harmful component (organic solvent) eliminates environmental pollution and health hazards while maintaining formulation stability through the use of surfactants and adjuvants that enable water-based dissolution of emamectin benzoate.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent changes the fundamental parameter of the solvent system from organic-based to water-based. By modifying the solvent type parameter and introducing specific surfactants and adjuvants, the formulation achieves both environmental friendliness and stability, resolving the contradiction between these two opposing requirements.

Inventive Principle:
Principle #35Parameter changes

2Manufacturing precision

If particle size of pesticidal technical material is reduced, then efficacy is improved, but manufacturing complexity increases

Engineering Contradiction:
Improveparticle size controlVSAvoidmanufacturing complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The patent incorporates dispersing agents and adjuvants in the formulation that pre-establish conditions for fine particle dispersion. These preliminary additives prevent particle aggregation and maintain small particle sizes throughout storage and application, achieving high efficacy without requiring complex post-manufacturing particle size control processes.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent introduces surfactants and dispersing agents as intermediary substances that mediate between the pesticidal technical material and water. These intermediaries enable the technical material to be dispersed at the molecular or fine particle level in water, achieving small effective particle sizes and high efficacy while simplifying manufacturing through straightforward mixing processes.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Object-affected harmful factors

If water-based formulations are used, then environmental friendliness is improved, but solubility of oil-soluble pesticides deteriorates

Engineering Contradiction:
Improveenvironmental friendlinessVSAvoidsolubility
Core Design Contradiction:
Object-affected harmful factorsVSQuantity of substance

Solution Approach 1:

The patent introduces surfactants and solubilizing adjuvants as intermediary substances that bridge the gap between water and oil-soluble pesticidal technical materials. These intermediaries have both hydrophilic and hydrophobic properties, enabling them to solubilize oil-soluble pesticides in water-based formulations, thereby achieving both environmental friendliness and adequate solubility.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent creates a composite water-based formulation system that combines water with specific surfactants, adjuvants, and emamectin benzoate. This composite material system leverages the properties of each component to achieve solubility of the oil-soluble pesticide in water while maintaining environmental friendliness, effectively resolving the solubility contradiction.

Inventive Principle:
Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The formulation achieves improved stability, reduced pesticide usage, extended shelf life, and enhanced efficacy while minimizing environmental impact, offering a more sustainable and cost-effective solution for pest control.

Implementation Method 1

The formulation is an aqueous solution comprising 1%-7% of emamectin benzoate, 1%-10% of agent A, 1%-6% of agent B, wherein the agent A is one or more selected from the group consisting of anionic surfactants

Methodology Applied
Scientific EffectSurfactant: Surfactant

Implementation Method 2

1%-6% of an antifreezing agent

Methodology Applied
Scientific EffectFreezing point depression: Freezing

Implementation Method 3

0.01%-0.1% of a defoaming agent

Methodology Applied
Scientific EffectFoam suppression: Antifoam

Data Source

PatentEP3106031B1Environmentally-friendly emamectin benzoate preparation and preparation method therefor
Publication Date: 2019.11.06 NANJING SCIENX BIOTECH CO LTD
  • EP3106031B1 patent drawingFigure 1~2
  • EP3106031B1 patent drawingFigure 3~4
  • EP3106031B1 patent drawingFigure 5~7

AI summary

An environmentally-friendly emamectin benzoate preparation. The environmentally-friendly emamectin benzoate preparation comprises emamectin benzoate and an agent A and does not comprise any organic solvent. The agent A is selected from one or more of an anionic surfactant containing sulfonic acid groups, an anionic surfactant containing sulfuric acid groups, and an anionic surfactant containing carboxy groups. The preparation may further comprise an agent B, a functional agent, a pesticide adjuvant and other ingredients. The preparation is preferably an aqueous solution or water-soluble powder. Also provided is a preparation method for the aqueous solution or water-soluble powder.