Embolisation Device Metallic Mesh Flow Restrictor

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Solution Overview

Problem

Embolisation devices face challenges in maintaining vessel occlusion performance when repeatedly transitioning between contracted delivery and expanded deployed configurations, with existing devices prone to reduced effectiveness due to tearing or unwanted folding of polymer membranes during deployment and recapture.

Innovation Solution

The embolisation device incorporates a self-expanding mesh flow restrictor with a metallic occluding mesh membrane attached to a stem, featuring a tubular section for enhanced anchoring and a crimping connector for secure attachment, allowing for reliable expansion and contraction without compromising occlusion rates.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If a polymer membrane is used for flow restriction, then the device can be manufactured with simpler materials, but the membrane is prone to tearing and unwanted folding during deployment and recapture transitions

Engineering Contradiction:
Improvemanufacturing simplicityVSAvoidmembrane integrity
Core Design Contradiction:
Ease of manufactureVSReliability

Solution Approach 1:

The patent combines a polymer membrane with a metallic mesh structure to create a composite flow restrictor. The metallic mesh provides structural support and prevents tearing while the polymer membrane maintains flow restriction functionality. This composite construction resolves the contradiction by incorporating both manufacturing simplicity (polymer) and reliability (metallic support) into a single device.

Inventive Principle:
Principle #40Composite materials

2Reliability

If an occluding membrane with high occlusion rate is selected, then vessel occlusion performance is improved, but the ability of the membrane to expand from contracted to deployed configuration is compromised due to tearing or unwanted folding

Engineering Contradiction:
Improveocclusion rateVSAvoidmembrane structural stability
Core Design Contradiction:
ReliabilityVSStability of the object's composition

Solution Approach 1:

The high occlusion rate polymer membrane is combined with a metallic mesh structure that provides structural stability during expansion and contraction. The metallic mesh acts as a reinforcement skeleton that prevents tearing and unwanted folding while allowing the membrane to maintain its high occlusion rate performance.

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The patent uses a flexible polymer membrane that can be folded during delivery and then expanded at the target site. The membrane's flexibility allows it to transition between contracted and deployed configurations while the metallic mesh provides the structural stability needed to prevent tearing during these transitions.

Inventive Principle:
Principle #30Flexible shells and thin films

3Adaptability or versatility

If the device is designed to be recaptured and redeployed multiple times, then delivery flexibility is improved, but the vessel occlusion performance deteriorates after repeated transitions

Engineering Contradiction:
Improvedelivery flexibilityVSAvoidocclusion performance
Core Design Contradiction:
Adaptability or versatilityVSReliability

Solution Approach 1:

The metallic mesh reinforcement provides durable structural support that withstands repeated expansion and contraction cycles without degradation. This allows the device to be recaptured and redeployed multiple times while maintaining consistent occlusion performance, resolving the contradiction between delivery flexibility and occlusion reliability.

Inventive Principle:
Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This configuration ensures consistent and high occlusion rates, reducing the risk of tearing and improving anchoring forces, even after multiple deployments and recaptures, by utilizing a metallic mesh that provides mechanical strength and support.

Implementation Method 1

a membrane support having a contracted delivery configuration and an expanded deployed configuration and comprising a self-expanding mesh extending at least radially outwardly from the stem

Methodology Applied
Scientific EffectSelf-expanding: Elasticity

Implementation Method 2

utilizing a metallic mesh that provides mechanical strength and support

Methodology Applied
Scientific EffectMechanical strength:

Implementation Method 3

a plurality of flexible bristles extending outwardly from the stem, the bristles having a contracted delivery configuration and an expanded deployed configuration in which the bristles extend at least radially outwardly from the stem to anchor the device in the lumen

Methodology Applied
Scientific EffectFriction: Friction

Data Source

PatentEP4099921B1Embolisation system for promoting clot formation
Publication Date: 2024.01.31 CLEASTREAM TECH LTD
  • EP4099921B1 patent drawingFigure 1A~1B
  • EP4099921B1 patent drawingFigure 1C
  • EP4099921B1 patent drawingFigure 2A~2B

AI summary

An embolisation device (100) for promoting clot formation in a bodily lumen (170), comprising a stem (110) and a plurality of flexible bristles (120) extending outwardly from the stem, the bristles having a contracted delivery configuration and an expanded deployed configuration in which the bristles extend at least radially outwardly from the stem to anchor the device in the lumen. The embolisation device comprises a flow restrictor configured to restrict flow through the bodily lumen. The flow restrictor comprises: a membrane support (135) having a contracted delivery configuration and an expanded deployed configuration and comprising a self-expanding mesh extending at least radially outwardly from the stem; and an occluding membrane (130) mounted on the membrane support (135). The occlusion rate of the occluding mesh membrane is greater than that of the membrane support. The flow restrictor is attached to the stem at a first longitudinal end, the flow restrictor further comprising an open second longitudinal end. The occluding membrane is configured to restrict flow through the lumen when the device is deployed and the membrane support is in the expanded deployed configuration.