Emphysema Threshold Determination via CT Value Clustering

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Solution Overview

Problem

The accuracy of detecting pulmonary features in medical images for emphysema diagnosis is low due to the dependence on user-input thresholds, which vary based on medical knowledge and experience, leading to inconsistent results across different users analyzing the same image.

Innovation Solution

A method is developed to automatically determine emphysema thresholds in pulmonary medical images by clustering CT values in lung lobe regions using Gaussian Mixture Models, dividing them into sub-regions, and calculating the intersection of their distribution functions to establish a consistent threshold for each lung lobe, reducing user dependency.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If user-input thresholds are used for determining emphysema regions, then the system can operate with simple automated processing, but the measurement precision deteriorates due to variability in user knowledge and experience

Engineering Contradiction:
Improveautomated processingVSAvoidemphysema region detection accuracy
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The system performs self-service by automatically determining emphysema thresholds through statistical analysis of CT value distributions without requiring user input. The automated threshold determination module calculates thresholds based on the intersection of distribution functions from clustering algorithms, eliminating dependency on user knowledge and experience while maintaining high measurement precision.

Inventive Principle:
Principle #25Self-service

2Adaptability or versatility

If different users input different thresholds based on their medical knowledge, then the system can accommodate various expert opinions, but the reliability deteriorates due to inconsistent results for the same image

Engineering Contradiction:
Improveaccommodation of user expertiseVSAvoidconsistency of detection results
Core Design Contradiction:
Adaptability or versatilityVSReliability

Solution Approach 1:

The system changes from using variable user-defined thresholds to using objectively calculated thresholds based on CT value distribution parameters. By computing thresholds from the intersection of distribution functions derived from clustering analysis, the system maintains adaptability to different lung conditions while ensuring consistent and reliable results across different users and images.

Inventive Principle:
Principle #35Parameter changes

3Device complexity

If manual threshold input by users is required, then the device complexity remains low, but the productivity deteriorates due to time-consuming operations and user dependency

Engineering Contradiction:
Improvesystem structureVSAvoiddetection efficiency
Core Design Contradiction:
Device complexityVSProductivity

Solution Approach 1:

The system performs preliminary action by automatically conducting clustering analysis and threshold determination before the user needs to make any decisions. The automated threshold determination module pre-calculates optimal thresholds based on the image data, eliminating the need for users to manually input thresholds and significantly improving detection efficiency without adding substantial device complexity.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS11478163B2Image processing and emphysema threshold determination
Publication Date: 2022.10.25 NEUSOFT MEDICAL SYST CO LTD
  • US11478163B2 patent drawing
  • US11478163B2 patent drawing
  • US11478163B2 patent drawing

AI summary

Methods, devices, systems and apparatus for determining emphysema thresholds for processing a pulmonary medical image are provided. In one aspect, a method includes: determining lung lobe regions in the pulmonary medical image, and, for each of the lung lobe regions, clustering CT values in the lung lobe region to divide the lung lobe region into a first sub region and a second sub region and acquiring a CT value corresponding to an intersection of a first CT value distribution function for the first sub region and a second CT value distribution function for the second sub region in the lung lobe region as an emphysema threshold for the lung lobe region.