Emulsion Composition Preventing Solid Precipitation Upon Dilution

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Solution Overview

Problem

Existing emulsion and microemulsion compositions face stability issues during long-term storage, often resulting in solid content precipitation when diluted with water, which affects their efficacy and usability.

Innovation Solution

A composition comprising an active ingredient with low water solubility, a water-insoluble solvent without an alcohol group, a nonionic surfactant, and a monohydric alcohol, specifically formulated to prevent solid content precipitation and enhance stability upon dilution with water.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If existing emulsion or microemulsion compositions are diluted with water for use, then the active ingredient becomes dispersed in water for application, but solid content precipitates during long-term storage reducing stability

Engineering Contradiction:
Improvestability of emulsion or microemulsionVSAvoidlong-term storage reliability
Core Design Contradiction:
Stability of the object's compositionVSReliability

Solution Approach 1:

The patent uses a composite emulsifier system combining nonionic surfactant (polyoxyethylene alkyl ether) and anionic surfactant (alkylbenzenesulfonate amine salt) to create a stable emulsion composition. This composite surfactant system prevents solid content precipitation during long-term storage while maintaining emulsion stability upon water dilution, resolving the contradiction between stability and reliability.

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The patent optimizes specific parameter ranges including surfactant concentrations (nonionic: 0.1-10% by mass, anionic: 0.01-5% by mass), active ingredient content (1-50% by mass), and water content (40-80% by mass) to achieve both long-term storage stability and reliable performance upon dilution. These parameter adjustments prevent precipitation while ensuring emulsion stability.

Inventive Principle:
Principle #35Parameter changes

2Ease of manufacture

If conventional emulsion compositions are formulated with simple surfactant systems, then the formulation is simple and easy to manufacture, but the emulsion stability is insufficient and solid content precipitates

Engineering Contradiction:
Improveease of composition formulationVSAvoidemulsion stability
Core Design Contradiction:
Ease of manufactureVSStability of the object's composition

Solution Approach 1:

The patent combines nonionic surfactants (polyoxyethylene alkyl ethers) with anionic surfactants (alkylbenzenesulfonate amine salts) in specific concentration ranges to create a composite emulsifier system. This composite approach provides sufficient emulsion stability to prevent solid content precipitation while maintaining relative simplicity in formulation and manufacturing processes.

Inventive Principle:
Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition achieves excellent stability and prevents solid content precipitation even after long-term storage, ensuring consistent efficacy and usability of the emulsion or microemulsion when diluted with water.

Implementation Method 1

component (C) at least one nonionic surfactant selected from the group consisting of a polyoxyalkylene alkyl ether, a polyoxyalkylene alkenyl ether, a polyoxyalkylene alkyl amino ether, and a polyoxyalkylene alkenyl amino ether

Methodology Applied
Scientific EffectSurfactant: Surfactant

Implementation Method 2

component (D) a monohydric alcohol having 8 to 12 carbon atoms

Methodology Applied
Scientific EffectEmulsion: Emulsion

Data Source

PatentUS10448642B2Composition for preparing emulsion or microemulsion
Publication Date: 2019.10.22 NIPPON SODA CO LTD

AI summary

A composition for preparing an emulsion or microemulsion, the composition including the following components (A) to (D):component (A): an active ingredient having a solubility in water at 20° C. of 200 ppm or less;component (B): a water-insoluble solvent having no alcohol group;component (C): at least one nonionic surfactant selected from the group consisting of a polyoxyalkylene alkyl ether, a polyoxyalkylene alkenyl ether, a polyoxyalkylene alkyl amino ether, and a polyoxyalkylene alkenyl amino ether; andcomponent (D): a monohydric alcohol having 8 to 12 carbon atoms.