Encoded Biosensor Circuit With Nonlinear Resistive Calibration Paths
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Solution Overview
Problem
Existing biosensor systems face challenges in efficiently coding information onto test strips for accurate analyte measurement, particularly due to limited information capacity and significant surface area usage, which can lead to incorrect analyte concentration readings if calibration information is not properly matched with the test strip lot.
Innovation Solution
The analyte test strip incorporates a non-conductive substrate with a serpentine configured primary resistive element and a secondary resistive element featuring taps, allowing for unique resistive paths with non-linear resistance distributions to encode attributes such as calibration data, type, and manufacturing information, enabling precise analyte measurement by the test meter.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Loss of information
If information is coded onto the test strip using prior art methods, then identification and calibration information can be provided to the test meter, but the amount of information that can be coded is severely limited and large amounts of test strip surface area are used
Solution Approach 1:
The patent changes the parameter of resistance distribution from linear to non-linear (exponential, power, or sinusoidal functions). This allows a limited physical space to encode a much larger amount of information through the mathematical properties of non-linear functions, resolving the contradiction between information capacity and surface area usage
Solution Approach 2:
The patent introduces a mathematical dimension (non-linear resistance distribution functions) to the physical resistance coding system. By using exponential, power, or sinusoidal relationships between resistance values and information encoding, the system transforms a one-dimensional physical space constraint into a multi-dimensional information encoding space, dramatically increasing coding capacity without additional surface area
2Measurement precision
If calibration information is not properly matched with the test strip lot, then the measurement device may not complete the analysis or may make wrong analysis of analyte concentration, but ensuring proper matching requires additional complexity in information coding and verification
Solution Approach 1:
The test meter measures the actual resistance values of the resistive elements on the test strip and compares them against expected values derived from non-linear distribution functions. This feedback mechanism automatically verifies calibration matching and prevents incorrect analysis, improving measurement precision while the automated nature of the verification keeps complexity manageable
Solution Approach 2:
The patent replaces manual calibration verification with an automated electrical measurement system. The test meter automatically measures resistance values and uses non-linear distribution algorithms to verify calibration matching, eliminating the need for manual ROM key insertion and user confirmation, thus improving precision without proportionally increasing complexity
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This solution allows for accurate and efficient encoding of information on the test strip, reducing human error in calibration and enhancing measurement precision by determining attributes based on resistance values, thereby ensuring precise analyte concentration readings.
Implementation Method 1
a primary resistive element on the non-conductive substrate having a first end and a second end, wherein the configuration of the primary resistive element is a serpentine configuration; and a secondary resistive element on the non-conductive substrate having a third end and a plurality of taps connected to the primary resistive element at a plurality of predetermined connection points
Data Source
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Figure 3A
AI summary
A sensor includes a non-conductive substrate and a circuit on the non-conductive substrate. The circuit includes a primary resistive element on the non-conductive substrate having a first end and a second end, wherein the primary resistive element has a predetermined configuration; a secondary resistive element on the nonconductive substrate having a plurality of taps connected to the primary resistive element at a plurality of predetermined connection points on the predetermined configuration, the plurality of predetermined connection points defining a plurality of unique resistive paths through at least a portion of the predetermined configuration; and the plurality of unique resistive paths having a plurality of resistance values, the plurality resistance values determined using a non-linear distribution function. A sensor is configured to perform at least one of quantitative and qualitative analysis of an analyte in a sample of fluid.