Co-Registering Endoluminal Data with Extraluminal Images

The patent merges extraluminal imaging data with endoluminal data by co-registering them to a common reference frame. The system combines fluoroscopic images with endoluminal measurements and images, integrating them spatially and temporally to create a unified view that improves diagnostic accuracy and therapeutic outcomes while managing system complexity through automated registration algorithms.

The patent introduces a co-registration system as an intermediary that bridges extraluminal and endoluminal data. This intermediary component automatically aligns and integrates the different data types by establishing spatial relationships between them, enabling comprehensive evaluation without requiring manual integration by the operator.

The patent implements feedback mechanisms where the system continuously monitors and adjusts the timing of endoluminal data acquisition based on synchronized extraluminal imaging events. This feedback loop ensures that data points are captured at the correct moments during the cardiac cycle or procedural sequence, maintaining high registration accuracy while optimizing acquisition speed through automated timing control.

The patent performs preliminary synchronization setup by establishing temporal and spatial relationships between imaging systems before data acquisition begins. Calibration markers and pre-programmed timing sequences are prepared in advance to ensure accurate co-registration without requiring real-time manual adjustment during the procedure.