Endoprosthesis Flexible Hinge Anti-Migration Connectors

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Solution Overview

Problem

Endoprostheses face challenges in preventing migration while allowing for tissue ingrowth for easy removal and maintaining luminal patency around bends in the body lumen, as existing solutions either cause trauma during removal or fail to maintain patency.

Innovation Solution

An endoprosthesis with a covered stent design featuring anti-migration connectors and a flexible hinge portion that allows tissue ingrowth through select areas and maintains patency around bends by using a polymeric cover that prevents ingrowth on strut rows but not on connectors, enabling secure placement and easy removal.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If a bare or partially covered endoprosthesis is used to allow tissue ingrowth for preventing migration, then anti-migration capability is improved, but trauma to the body lumen increases during removal

Engineering Contradiction:
Improveanti-migration capabilityVSAvoidtrauma to body lumen during removal
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The endoprosthesis applies local quality by having different coverage characteristics in different regions: the first and second portions have full coverage to prevent migration, while the third portion has selective openings to allow controlled tissue ingrowth. This localized differentiation resolves the contradiction by providing anti-migration capability where needed while minimizing trauma in removal zones.

Inventive Principle:
Principle #3Local quality

2Ease of operation

If a fully covered endoprosthesis is used to facilitate removal by preventing tissue ingrowth, then ease of removal is improved, but anti-migration capability deteriorates

Engineering Contradiction:
Improveease of removalVSAvoidanti-migration capability
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The device implements local quality by creating a spatial differentiation of coverage: fully covered sections (first and second portions) provide migration prevention, while the third portion features selective openings that allow controlled tissue interaction. This resolves the contradiction by providing both ease of removal in specific zones and anti-migration capability in others.

Inventive Principle:
Principle #3Local quality

3Strength

If a stiff endoprosthesis is used to maintain luminal patency, then structural support is improved, but adaptability to bends in the body lumen deteriorates

Engineering Contradiction:
Improvestructural support for luminal patencyVSAvoidadaptability to bends
Core Design Contradiction:
StrengthVSAdaptability or versatility

Solution Approach 1:

The endoprosthesis applies segmentation by dividing the structure into multiple portions (first, second, and third portions) with different structural characteristics. The first and second portions provide structural support for luminal patency, while the third portion with selective openings provides flexibility for bending. This segmentation resolves the contradiction between strength and adaptability.

Inventive Principle:
Principle #1Segmentation

4Strength

If multiple endoprostheses are used to cover bends in the body lumen, then luminal patency is improved, but device complexity increases

Engineering Contradiction:
Improveluminal patency around bendsVSAvoidnumber of endoprostheses required
Core Design Contradiction:
StrengthVSDevice complexity

Solution Approach 1:

The invention merges multiple functions into a single integrated endoprosthesis structure. The device combines luminal patency maintenance (through the first and second portions) with bend adaptability (through the third portion with selective openings) in one unified structure, eliminating the need for multiple separate endoprostheses and reducing overall device complexity.

Inventive Principle:
Principle #5Merging (Combining)

Data Source

PatentEP3203943B1Stent with flexible hinge
Publication Date: 2023.04.19 BOSTON SCIENTIFIC SCIMED INC
  • EP3203943B1 patent drawingFigure 1
  • EP3203943B1 patent drawingFigure 2
  • EP3203943B1 patent drawingFigure 3

AI summary

An endoprosthesis may include an expandable tubular framework (12) expandable from a compressed state to an expanded state and include a plurality of strut rows (20), wherein adjacent strut rows define interstices spacing the adjacent strut rows apart, and a plurality of connectors (22) extending across the interstices and interconnecting adjacent strut rows, at least some of the plurality of connectors defining a flexible hinge portion. The lengths of the interstices between adjacent strut rows may vary along the length of the expandable tubular framework. The plurality of connectors extend radially outward beyond an outer diameter of the plurality of strut rows in the expanded state. The plurality of connectors are configured to engage a wall of a body lumen in the expanded state to inhibit migration of the endoprosthesis subsequent implanting the endoprosthesis in the body lumen.