Endoscopic Electrode Access for Minimally Invasive Neurophysiological Mapping

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Solution Overview

Problem

Current neurosurgical endoscopy lacks tools for neurophysiological recording and stimulation of ventricular surfaces, preventing the transfer of neurophysiological advantages from open microsurgery to minimally invasive procedures.

Innovation Solution

A device for neurophysiological analysis comprising a sensitive element, such as a single-pole or two-pole electrode, which can be inserted into the work channel of a rigid or elastic endoscope for direct contact with nerve structures, allowing recording and stimulation during endoscopic procedures.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If open microsurgery is used to perform neurophysiological mapping and monitoring, then precise localization of functional areas and real-time analysis of neurological functions can be achieved, but the invasiveness of surgery increases significantly requiring removal of a significant portion of the skull

Engineering Contradiction:
Improveprecise localization of functional areasVSAvoidinvasiveness of surgery
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The sensitive element (electrode) is inserted through the work channel of the endoscope, nesting the neurophysiological analysis tool within the minimally invasive endoscopic system. This allows the electrode to reach deep brain regions through a small craniotomy while the endoscope provides the access pathway, combining the benefits of both approaches.

Inventive Principle:
Principle #7Nested doll (Nesting)

Solution Approach 2:

The endoscope acts as an intermediary tool that enables the sensitive element to access deep brain regions without requiring large skull openings. The endoscope's work channel serves as a conduit, allowing the electrode to reach the target area through a minimally invasive craniotomy while maintaining the capability for neurophysiological mapping.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Object-affected harmful factors

If endoscopic procedures are used to minimize invasiveness, then patient safety and reduced surgical trauma are achieved, but the capability to perform neurophysiological recording and stimulation of ventricular surfaces is lost

Engineering Contradiction:
Improveinvasiveness of surgeryVSAvoidcapability for neurophysiological recording and stimulation
Core Design Contradiction:
Object-affected harmful factorsVSAdaptability or versatility

Solution Approach 1:

The device combines multiple functions within a single integrated system: the endoscope provides visualisation and access, while the sensitive element inserted through its work channel enables neurophysiological recording and stimulation. This multi-functional approach allows endoscopic procedures to maintain minimally invasive benefits while gaining neurophysiological capabilities previously only available through open surgery.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The sensitive element is nested within the endoscope's work channel, allowing the minimally invasive endoscopic approach to simultaneously perform both visualisation and neurophysiological analysis functions that were previously requiring separate open surgical procedures.

Inventive Principle:
Principle #7Nested doll (Nesting)

3Reliability

If a significant portion of the skull is removed to perform neurophysiological mapping, then real-time analysis of neurological functions during surgery can be performed, but the surgical procedure becomes significantly more invasive and time-consuming

Engineering Contradiction:
Improvereal-time analysis of neurological functionsVSAvoidsurgical procedure time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

By nesting the sensitive element within the endoscope's work channel, the system enables real-time neurophysiological analysis to be performed through the existing endoscopic access pathway, eliminating the need for additional skull openings and extending surgical procedures. The electrode can be positioned and used concurrently with the endoscopic visualisation.

Inventive Principle:
Principle #7Nested doll (Nesting)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables minimally invasive neurophysiological mapping and monitoring by allowing direct contact with nerve structures, reducing the risk of neurological damage and facilitating precise localization of functional areas during surgery.

Implementation Method 1

a sensitive element which is of the rigid or elastic type, is formed of a single-pole or two-pole electrode, and can be inserted into a work channel of the endoscope

Methodology Applied
Scientific EffectElectrical signal detection: Conduction (electrical)

Implementation Method 2

allows recording and stimulation during endoscopic procedures

Methodology Applied
Scientific EffectElectrical stimulation: Electric Field

Data Source

PatentEP4590178B1Device for neurophysiological analysis in the field of neurosurgical endoscopy and endoscopic group including the device and an endoscope
Publication Date: 2026.02.25 UNIV DEGLI STUDI DI VERONA
  • EP4590178B1 patent drawingFigure 1
  • EP4590178B1 patent drawingFigure 2~3
  • EP4590178B1 patent drawingFigure 4~6

AI summary

Device (50) for the neurophysiological analysis of an anatomical region of interest of a patient in the field of neurosurgical endoscopy, the device (50) comprising: a handgrip (52); and a sensitive element (56) having a first (56a) and a second end (56b) opposite to each other along a main extension direction (58) of the sensitive element (56), the sensitive element (56) being coupled in a releasable manner with the handgrip (52) through the first end (56a). The sensitive element (56) comprises a single-pole electrode (56') or a two-pole electrode (56''). The sensitive element (56) is either rigid or elastic in flexions transverse to the main extension direction (58).