Endoscopic Patch Delivery with Controlled Release for Gastrointestinal Wounds
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Solution Overview
Problem
Existing treatments for gastrointestinal tract wounds, such as perforations and bleeding defects, are invasive and have high morbidity and mortality rates, necessitating less invasive endoscopic delivery options.
Innovation Solution
A medical device comprising a first tube, a second tube to sheath the first tube, an expandable device, a patch surrounding the expandable device, and a connector to hold and release the patch, allowing for endoscopic delivery and deployment of a biocompatible adhesive or therapeutic agent patch in the gastrointestinal tract.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If surgical re-operation is used to treat gastrointestinal tract wounds, then effective treatment can be achieved, but the treatment becomes invasive with high morbidity and mortality rates
Solution Approach 1:
The patent replaces the mechanical surgical re-operation system with an endoscopic delivery system that uses a delivery device to transport and deploy a patch at the target site within the gastrointestinal tract, eliminating the need for invasive surgery while maintaining treatment effectiveness
Solution Approach 2:
The patent introduces a patch as an intermediary treatment aid that is delivered endoscopically to the target site. The patch serves as a mediator between the delivery device and the wounded tissue, providing effective treatment without requiring direct surgical intervention
2Object-affected harmful factors
If a patch is delivered endoscopically to the target site, then less invasive treatment is achieved, but the patch must be securely held during delivery and then released for deployment
Solution Approach 1:
The connector's attachment parameter changes from a secured state during delivery to a released state at the target site. The connector is designed to transition from holding the patch firmly during endoscopic delivery to releasing it for deployment, achieving less invasive treatment with controlled device complexity
Solution Approach 2:
The connector mechanism is designed to be dynamic, transitioning from a secured configuration during delivery to a released configuration at the target site. This dynamic behavior allows the system to maintain the patch securely during transport while enabling easy release for deployment, balancing reduced invasiveness with manageable device complexity
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Facilitates less invasive treatment of gastrointestinal tract wounds by enabling the endoscopic delivery and deployment of a biocompatible adhesive or therapeutic agent patch, promoting natural healing with reduced morbidity and mortality.
Implementation Method 1
The soluble adhesive may be configured to dissolve when the second tube uncovers the patch and the expandable device, and the patch may be exposed to a solvent, thereby releasing the patch from the connector and the expandable device.
Data Source
Figure 1A~1B
Figure 1C~1D
Figure 2A~2B
AI summary
A medical device comprising a first tube, a second tube configured to sheath at least a portion of the first tube and configured to translate along a length of the first tube, an expandable device at a distal portion of the first tube, the expandable device having a collapsed state and an expanded state, a patch surrounding at least a portion of an outer surface of the expandable device, and a connector for holding the patch to the expandable device when the second tube covers the patch and the expandable device and for releasing the patch from the expandable device after the second tube uncovers the patch and the expandable device.