Endoscopic Dry Powder Delivery via Gas-Powder Mixing Chamber
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Solution Overview
Problem
Current methods for delivering dry powder medications through endoscopic cannulas face challenges such as occlusion due to resistance in the narrow cannula and mixing with excess liquid and pressurized air, limiting precise delivery to internal tissue sites during minimally invasive surgeries.
Innovation Solution
An internal dry powder delivery system comprising an elongated tubular delivery channel with a gas-powder chamber that mixes dry powder with pressurized gas, allowing continuous feeding and spraying of the mixture onto the target site, and a dual gas channel system to maintain pressure and prevent reflux, enabling precise delivery through the endoscope's working channel.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If dry powder is delivered through a narrow endoscopic cannula, then the medication can reach internal tissue sites, but occlusion occurs due to resistance in the cannula
Solution Approach 1:
A gas-powder mixing chamber is introduced as an intermediary device between the powder source and the endoscopic cannula. Dry powder is mixed with pressurized gas in this chamber to create a gas-powder mixture that flows more smoothly through the narrow cannula, reducing occlusion while maintaining delivery precision to internal tissue sites.
2Ease of operation
If liquid is used to transport dry powder through the cannula, then powder delivery is enabled, but mixing with excess liquid causes occlusion and reduces effectiveness
Solution Approach 1:
The system uses pressurized gas instead of liquid to transport dry powder through the endoscopic cannula. The gas-powder mixture is propelled by pneumatic pressure, enabling effective powder delivery without the occlusion problems caused by liquid mixing, while maintaining ease of operation during minimally invasive procedures.
3Force
If pressurized air is used to deliver powder, then delivery force is improved, but excess air causes occlusion at the tip
Solution Approach 1:
The gas-powder mixing chamber is designed to provide just enough pressurized gas to propel the powder through the cannula without excessive gas flow. This partial action approach delivers sufficient force for reliable powder transport while preventing tip occlusion by controlling the gas-to-powder ratio in the mixture.
4Ease of operation
If capsule or pill forms are used, then medication can be administered, but dosage control is imprecise due to dilution by gastric and intestinal juices
Solution Approach 1:
The invention extracts the medication from traditional capsule or pill forms and delivers it as dry powder directly to the target tissue site through the endoscopic cannula. This eliminates the dilution effect of gastric and intestinal juices, enabling precise dosage control while maintaining ease of administration during minimally invasive procedures.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables direct and precise application of dry powder medications to internal sites, overcoming occlusion issues and ensuring effective delivery of biomaterials for hemostasis, tissue repair, and other therapeutic purposes during minimally invasive procedures.
Implementation Method 1
a pressurized gas feeder producing pressurized gas in the gas-powder chamber mixing with the dry powder therein to form a mixture of dry powder and pressurized gas
Implementation Method 2
a pressurized gas feeder producing pressurized gas in the gas-powder chamber mixing with the dry powder therein to form a mixture of dry powder and pressurized gas for blowing into the delivery channel
Data Source
AI summary
An internal dry powder delivery system through a working channel of an endoscopic cannula for directly applying the powder form medication to an internal tissue/organ site, includes an elongated tubular delivery channel and a powder supply device for producing pressurized gas mixing with the dry powder for feeding to form a mixture of dry powder and pressurized gas delivering to an internal tissue/organ site through the delivery channel via endoscopic cannula. It ensures a smooth powder release by preventing liquid from accumulation at the tip of the delivery channel and offers physicians a new powder form drug delivery method via endoscope. Also, it offers new minimal invasive application by directly and precisely applying the powder format drug to the internal sites of human gastrointestinal organ via endoscope to achieve hemostasis, anti-inflammation, anti-ulcer and anti-tumor treatment, etc.