Low- and High-Energy Difference Imaging for Temporal Contrast Permeation

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Solution Overview

Problem

Existing contrast imaging technologies require a large number of radiation images to observe the temporal change of a contrast medium permeation, which is inefficient and potentially increases exposure dose.

Innovation Solution

A method involving a radiography apparatus that captures low-energy and high-energy images at different timings, generating difference images to observe the temporal change of contrast medium permeation, with the low-energy images captured less frequently than high-energy images, and displaying these images as a moving series.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If contrast imaging is performed by capturing multiple low-energy images and multiple high-energy images at different timings to observe temporal change of contrast medium, then the temporal change of contrast amount can be observed, but the number of radiation images becomes large

Engineering Contradiction:
Improvetemporal change observationVSAvoidnumber of radiation images
Core Design Contradiction:
Measurement precisionVSQuantity of substance

Solution Approach 1:

The patent segments the imaging process into two distinct energy groups: low-energy images (first energy group) and high-energy images (second energy group). By categorizing images based on energy levels and selectively combining them, the system reduces the total number of images needed while maintaining the ability to observe temporal contrast changes. This segmentation allows the processor to generate difference images using only representative low-energy images and multiple high-energy images, rather than requiring equal numbers of both types.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent extracts and utilizes only the necessary high-energy images for generating difference images, while using a single representative low-energy image. The processor extracts contrast information by comparing high-energy images against the low-energy baseline, thereby observing temporal changes without capturing and processing an equal number of low-energy images. This extraction approach reduces the overall image quantity while preserving diagnostic information.

Inventive Principle:
Principle #2Taking out (Extraction)

2Measurement precision

If multiple radiation images are captured to display difference image as moving image, then temporal change of contrast medium can be observed, but exposure dose increases

Engineering Contradiction:
Improvetemporal change observationVSAvoidexposure dose
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The patent segments radiation exposure into two energy levels and applies them differently: low-energy radiation is applied once to capture a baseline image, while high-energy radiation is applied multiple times to capture temporal changes. This segmentation strategy reduces cumulative exposure dose by minimizing low-energy exposures (which contribute more to dose) while relying on high-energy images for temporal observation, thereby lowering overall harmful radiation exposure.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent changes the energy parameter of radiation between different imaging phases. By switching from low-energy to high-energy radiation and adjusting the number of exposures at each energy level, the system optimizes the balance between diagnostic quality and exposure dose. The processor generates difference images by combining images at different energy levels, allowing temporal observation with reduced total dose through parameter optimization.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables observation of contrast medium temporal change with a reduced number of radiation images, reducing exposure dose and enhancing image clarity by focusing on contrast medium permeation.

Implementation Method 1

acquires a low-energy image captured by a radiography apparatus by emitting radiation having first energy to a subject into which a contrast medium has been injected, and each of a plurality of high-energy images captured by the radiography apparatus at different timings by emitting radiation having second energy higher than the first energy to the subject

Methodology Applied
Scientific EffectRadiation absorption: Absorption (EM radiation)

Data Source

PatentUS12350086B2Information processing apparatus, information processing method, and information processing program
Publication Date: 2025.07.08 FUJIFILM CORP
  • US12350086B2 patent drawing
  • US12350086B2 patent drawing
  • US12350086B2 patent drawing

AI summary

An information processing apparatus includes at least one processor that is configured to: acquire a low-energy image captured by a radiography apparatus by emitting radiation having first energy to a subject into which a contrast medium has been injected, and each of a plurality of high-energy images captured by the radiography apparatus at different timings by emitting radiation having second energy higher than the first energy to the subject into which the contrast medium has been injected, and generate a plurality of difference images showing a difference between the low-energy image and each of the plurality of high-energy images.