Enzyme Compositions Using Cell-Wall Hydrolysis for Crop Disease Control

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Solution Overview

Problem

Current methods for managing phytopathogenic infestations and infections in plants are inadequate in efficacy and sustainability, leading to significant crop losses and yield reductions.

Innovation Solution

The use of specific enzyme treatments that target various phytopathogens, applied through foliar, seed, or soil-compatible carriers, to inhibit pathogen growth and enhance plant health and yield.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If current methods for managing phytopathogenic infestations are used, then crop production continues, but efficacy is inadequate and sustainability is compromised

Engineering Contradiction:
Improvedisease control efficacyVSAvoidcrop losses and yield reductions
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent changes the chemical parameters of pathogen management by using enzyme compositions with specific activities (cellulase, pectinase, chitinase, protease) instead of conventional chemicals. These enzymes target specific pathogen cell wall components, providing effective disease control while maintaining sustainability through biodegradable, plant-safe formulations.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The enzyme compositions act as intermediaries between the plant and pathogen, selectively degrading pathogen cell walls without harming the plant. The enzymes mediate the interaction by breaking down specific pathogen structures (cellulose, pectin, chitin, protein) while the plant remains unaffected, thereby controlling disease without the harmful effects of conventional pesticides.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If conventional phytopathogen management methods are applied, then pathogen growth is targeted, but sustainability is compromised

Engineering Contradiction:
Improvepathogen growth inhibitionVSAvoidenvironmental sustainability
Core Design Contradiction:
ReliabilityVSStability of the object's composition

Solution Approach 1:

The enzyme compositions are designed as biodegradable, short-lived agents that perform their pathogen-control function and then naturally decompose. Unlike persistent conventional pesticides, these enzymes break down after use, preventing environmental accumulation and maintaining sustainability while effectively inhibiting pathogen growth during their active period.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Solution Approach 2:

The patent changes the environmental stability parameter by using naturally degradable enzyme proteins instead of persistent synthetic chemicals. The enzymes maintain their pathogen-inhibiting function under specific conditions but naturally decompose under environmental conditions, providing effective pathogen control while ensuring environmental sustainability through their transient nature.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If enzyme treatments are applied to inhibit pathogen growth, then disease control improves, but potential adverse effects on plants must be minimized

Engineering Contradiction:
Improvedisease controlVSAvoidadverse effects on plants
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The enzyme compositions exhibit local quality by targeting specific pathogen structures (cell wall components) rather than acting broadly on all biological material. Each enzyme (cellulase, pectinase, chitinase, protease) selectively degrades specific pathogen cell wall components, providing effective disease control while leaving plant tissues unaffected due to their different structural compositions.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The enzymes serve as selective intermediaries that distinguish between pathogen and plant tissues. They mediate the interaction by recognizing and degrading pathogen-specific cell wall components while leaving plant cells intact, thereby providing disease control without causing adverse effects on the host plant.

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The enzyme treatments demonstrate significant disease control and growth enhancement, reducing pathogen spread and improving plant health and yield, with minimal adverse effects on plants.

Implementation Method 1

enzymes including, but not limited to, cellulase, pectinase, chitinase, and protease, and combinations thereof

Methodology Applied
Scientific EffectHydrolysis: Hydrolysis

Data Source

PatentUS20250311734A1Compositions and Methods for Preventing, Treating, Suppressing and/or Eliminatting Phytopathogenic Infestations and Infections
Publication Date: 2025.10.09 NOVOZYMES AS
  • US20250311734A1 patent drawing
  • US20250311734A1 patent drawing
  • US20250311734A1 patent drawing

AI summary

The present disclosure provides proteins useful for preventing, treating, suppressing and/or eliminating infestations and infections of plants by various phytopathogenic pests, as well as formulations comprising such proteins, polynucleotides encoding such proteins, organisms expressing such proteins, and methods of using such proteins, formulations, polynucleotides and organisms in agriculture and other fields of endeavor.