Epigenetic Analysis System for Rapid Health Check via Genomic Segmentation

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Solution Overview

Problem

Current methods for identifying the effects of pathogens and tracking health changes are inefficient, relying on symptomatic reporting and impractical real-time analysis, which hinders early detection and prevention of epidemics or pandemics.

Innovation Solution

The implementation of anatomical modularization and modified hash function approaches for epigenetic analysis, enabling rapid sequencing and correlation with baseline medical status, facilitating real-time health checks and bio-surveillance.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If traditional epigenetic sequencing methods are used to identify disease effects, then comprehensive health analysis can be achieved, but real-time analysis becomes impractical due to significant memory storage and computing power requirements

Engineering Contradiction:
Improvehealth analysis accuracyVSAvoidanalysis time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent segments the genome into smaller genomic regions and assigns each region a unique identifier, transforming complex genomic data into manageable discrete units. This segmentation enables efficient storage and rapid comparison without requiring comprehensive sequencing of entire genomes, thus reducing analysis time while maintaining health detection accuracy.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent creates simplified copies of genomic information through unique identifiers that represent specific genomic regions. Instead of storing and processing complete genomic sequences, the system uses these identifier copies to track and compare epigenetic modifications, dramatically reducing computational requirements while preserving the ability to detect disease-related changes.

Inventive Principle:
Principle #26Copying

2Reliability

If comprehensive biomarker tracking is implemented for early disease detection, then health monitoring capability is improved, but computational complexity and resource requirements increase significantly

Engineering Contradiction:
Improvedisease detection reliabilityVSAvoidcomputational system complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent extracts only the essential information needed for disease detection by assigning unique identifiers to specific genomic regions. This extraction process isolates the critical data elements (epigenetic modifications in disease-associated regions) from the overwhelming complexity of complete genomic data, enabling reliable disease detection with reduced computational complexity.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent transforms genomic data from continuous sequence information into discrete parameter representations (unique identifiers for genomic regions). This parameter change converts complex biological data into a format that is computationally efficient to store and analyze, maintaining detection reliability while reducing system complexity.

Inventive Principle:
Principle #35Parameter changes

3Productivity

If real-time bio-surveillance is implemented to track pathogen spread, then early warning capability is enhanced, but data processing requirements and overhead become prohibitively high

Engineering Contradiction:
Improvedisease detection speedVSAvoidprocessing overhead
Core Design Contradiction:
ProductivityVSUse of energy by moving object

Solution Approach 1:

The patent performs preliminary actions by pre-segmenting the genome and assigning unique identifiers to genomic regions before actual disease detection is needed. This advance preparation creates a ready-to-use framework that enables rapid real-time surveillance without requiring intensive processing during actual monitoring, thus enhancing detection speed while reducing ongoing processing overhead.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS20230124917A1Systems and methods for monitoring and identifying physiological impact events
Publication Date: 2023.04.20 CENT INTELLIGENCE AGENCY
  • US20230124917A1 patent drawing
  • US20230124917A1 patent drawing
  • US20230124917A1 patent drawing

AI summary

The present subject matter addresses a process and testing procedures for establishing a baseline medical status and tracking changes to an individual's immune system with exposure to impact events over time. In particular, the processes described herein establish a baseline medical status for the individual and, through periodic or otherwise initiated medical sampling, map the changes and development of an individual's immune system using biomarkers for exposures. These biomarkers are cataloged as part of an individual medical profile and can assist in bio-surveillance efforts to identify biomarkers for global under-reported and under-researched pathogens through the study of individuals originating from or visiting highly infectious areas. In particular, the present subject matter relates to a method for the diagnosis of an impact event to physiology as well as a system for implementing such analysis and providing treatment options and alerts.