Epsilon-Polylysine and Aromatic Compounds for Skin Microflora Preservation
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Solution Overview
Problem
Current cosmetic and dermatological products face challenges in effectively addressing impure skin, body odor, and microbial infections without impairing skin health, as existing antimicrobial substances often disrupt the skin's natural microflora and have limitations in duration and compatibility with other ingredients.
Innovation Solution
The use of active ingredient combinations comprising ε-polylysine with aromatic esters, aldehydes, or alcohols, such as Hexyl Cinnamal, benzyl acetate, and phenylethyl alcohol, which provide a synergistic antimicrobial effect while being gentle on the skin and compatible with various cosmetic formulations.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional antimicrobial substances are used to eliminate bacteria and microorganisms, then the effectiveness against pathogenic germs is improved, but the skin's natural microflora is disrupted and skin health is impaired
Solution Approach 1:
The patent changes the chemical parameters of the antimicrobial agent by using ε-polylysine, a biocompatible polycation with specific molecular weight and degree of polymerization (DP 10-100), instead of conventional harsh antimicrobials. This parameter change allows effective antimicrobial action while maintaining skin compatibility and preserving beneficial microflora.
Solution Approach 2:
The patent creates a composite antimicrobial system by combining ε-polylysine with aromatic esters, aldehydes, and/or alcohols. This composite approach enhances the antimicrobial effectiveness against pathogenic germs while the aromatic components contribute to skin compatibility and odor management, resolving the contradiction between effectiveness and microflora preservation.
2Object-generated harmful factors
If the entire microflora of the skin is reduced to eliminate odor-causing microorganisms, then body odor is effectively reduced, but the natural protective microflora is also eliminated
Solution Approach 1:
The patent applies local quality by targeting specific odor-causing microorganisms while preserving the overall skin microflora balance. The ε-polylysine/aromatic compound combination selectively reduces problematic bacteria responsible for body odor without eliminating beneficial microorganisms, thus maintaining the skin's natural protective barrier.
Solution Approach 2:
The patent changes the concentration parameters and chemical nature of antimicrobial agents to achieve selective action. By using ε-polylysine at optimized concentrations combined with aromatic compounds, the system achieves effective odor reduction while maintaining microflora balance and protective functions.
3Object-generated harmful factors
If astringents are used to prevent sweat formation, then body odor is reduced, but skin proteins are denatured and heat balance is drastically affected
Solution Approach 1:
The patent substitutes the mechanical/chemical action of astringents (which cause protein precipitation and vasoconstriction) with a biological antimicrobial mechanism. The ε-polylysine/aromatic compound system works by interfering with microbial cell membranes and metabolism, achieving odor reduction without protein denaturation or heat balance disruption.
4Object-generated harmful factors
If perfumes are used to mask body odor, then body odor is concealed, but the mixture of body odor and perfume scent smells unpleasant and active ingredients may react with perfume components
Solution Approach 1:
The patent converts the harmful body odor into a benefit by using the aromatic esters, aldehydes, and/or alcohols as dual-function ingredients. These aromatic compounds serve both as antimicrobial agents that reduce odor-causing microorganisms and as fragrance components that provide a pleasant scent, eliminating the need for separate perfumes and avoiding incompatibility reactions.
Data Source
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AI summary
The invention relates to active ingredient combinations comprising: a) e-polylysine (epsilon-polylysine), and b) one or more aromatic esters, aldehydes and/or alcohols.