ESI Visualization Virtual Electrodes Seizure Analysis

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Solution Overview

Problem

Current electrical source imaging (ESI) visualizations are not suitable for reviewing longer events like seizures, as they are primarily designed for transient events and lack effective representation over extended time periods, limiting their diagnostic utility in epilepsy and other neurological conditions.

Innovation Solution

The method involves generating virtual electrodes from ESI waveforms and placing them at three-dimensional locations within the brain or on the scalp, allowing for direct measurement and visualization, which enables better representation and analysis of brain activity over longer periods, familiar to electroencephalographers, and can simulate stereo EEG probes for invasive recordings.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Duration of action of moving object

If traditional ESI visualization methods are used, then transient events like spikes can be effectively analyzed, but longer events such as seizures cannot be properly reviewed

Engineering Contradiction:
Improvereview time periodVSAvoidvisualization suitability
Core Design Contradiction:
Duration of action of moving objectVSEase of operation

Solution Approach 1:

The patent introduces a time dimension to the traditional ESI visualization by generating time-series waveforms from ESI data. Instead of only spatial voxel representations, the system creates waveform displays that show how brain activity evolves over time, enabling effective review of prolonged events like seizures while maintaining the ability to analyze transient spikes.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Loss of information

If ESI data is presented using traditional voxel-based colored scale representations, then spatial distribution is visualized, but temporal dynamics over long periods are not effectively captured

Engineering Contradiction:
Improvetemporal dynamics informationVSAvoidvisualization method complexity
Core Design Contradiction:
Loss of informationVSDevice complexity

Solution Approach 1:

The patent segments the ESI data into discrete time-series waveforms that can be analyzed individually or in sequences. By breaking down the continuous ESI dataset into manageable waveform segments, the system preserves temporal dynamics information while maintaining analytical simplicity for clinicians reviewing long-duration brain activity.

Inventive Principle:
Principle #1Segmentation

3Measurement precision

If virtual electrodes are generated from ESI waveforms, then direct measurement at 3D locations is enabled, but the system complexity increases

Engineering Contradiction:
Improvesignal source localizationVSAvoidprocessing system complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent creates virtual electrodes as computational copies of physical electrode positions, placed at specific 3D locations within the brain model. These virtual electrodes replicate the measurement function without requiring physical implantation, enabling precise signal source localization through software-based waveform generation and analysis.

Inventive Principle:
Principle #26Copying

Data Source

PatentUS20210369181A1Method And System For Visualizing Data From Electrical Source Imaging
Publication Date: 2021.12.02 PERSYST DEVELOPMENT CORP
  • US20210369181A1 patent drawing
  • US20210369181A1 patent drawing
  • US20210369181A1 patent drawing

AI summary

A method for visualizing data from electrical source imaging (ESI) is disclosed herein. The method converts the ESI into a plurality of ESI waveforms. The method generates a virtual electrode from the plurality of ESI waveforms. The method places the virtual electrode at a three-dimensional (3D) location of a representation of the patient's brain or on the surface of the scalp. The method receives a direct measurement of the virtual electrode at the 3D location.