Automatic ESR Analyzer Using Infrared Detection and Rotating Blending

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Solution Overview

Problem

The traditional Westergren method for erythrocyte sedimentation rate (ESR) measurement is labor-intensive, time-consuming, and poses health risks due to direct contact with blood samples, with potential for inaccurate results and requiring manual handling and specialized tubes.

Innovation Solution

A full-automatic erythrocyte sedimentation rate analyzer with a blending device and infrared detection system that automates sample blending and measurement, using closed containers to minimize direct contact and employing a barcode scanning and data collection module for efficient and accurate ESR analysis.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If manual blending and reading method is used, then operation simplicity is maintained, but operator safety deteriorates due to direct contact with blood samples

Engineering Contradiction:
Improveoperation simplicityVSAvoidoperator safety
Core Design Contradiction:
Ease of operationVSObject-affected harmful factors

Solution Approach 1:

The patent introduces an automatic blending device with a rotating rack that holds multiple sedimentation tubes. This intermediary mechanism performs the blending operation automatically, eliminating direct contact between the operator and blood samples while maintaining operational simplicity through automated rotation and positioning.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent replaces manual mechanical blending with an automated rotating rack system. The rotation device automatically positions and blends samples in sedimentation tubes, substituting the manual mechanical action with an automated mechanical system that improves operator safety.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Device complexity

If manual reading of sedimentation scale is used, then device complexity is reduced, but measurement precision deteriorates due to artificial difference

Engineering Contradiction:
Improvedevice complexityVSAvoidmeasurement precision
Core Design Contradiction:
Device complexityVSMeasurement precision

Solution Approach 1:

The patent replaces manual visual reading with an optical detection system. Infrared transmitting and receiving devices automatically measure the sedimentation scale, eliminating human error and improving measurement precision while managing device complexity through integrated optical components.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent utilizes the optical properties of blood samples, detecting changes in light transmission as erythrocytes sediment. The infrared detection system measures the position of the sedimentation interface by detecting optical changes, providing precise automated measurement.

Inventive Principle:
Principle #32Color changes

3Measurement precision

If 60 minute sedimentation time is used, then measurement accuracy is maintained, but productivity deteriorates due to overlong detection time

Engineering Contradiction:
Improvemeasurement accuracyVSAvoiddetection efficiency
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The patent implements continuous automated monitoring of sedimentation processes. Multiple sedimentation tubes are monitored simultaneously by the infrared detection system, which continuously measures sedimentation progress. This allows for earlier termination points to be identified accurately, reducing overall detection time while maintaining precision through continuous data collection.

Inventive Principle:
Principle #20Continuity of useful action

Solution Approach 2:

The patent performs preliminary automated blending and positioning of multiple samples before detection begins. The rotating rack pre-positions all sedimentation tubes, and the system is ready for immediate detection, eliminating setup time and enabling faster throughput while maintaining accurate measurement of the full sedimentation process.

Inventive Principle:
Principle #10Preliminary action

4Object-affected harmful factors

If automatic blending device is introduced, then operator safety is improved by reducing contact, but device complexity increases

Engineering Contradiction:
Improveoperator safetyVSAvoiddevice complexity
Core Design Contradiction:
Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

The rotating rack device serves multiple functions: it holds multiple sedimentation tubes, performs automated blending through rotation, positions tubes for detection, and enables sequential processing of multiple samples. This multi-functionality justifies the added complexity by consolidating several operations into a single automated mechanism.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent combines the blending mechanism, sample holding rack, and positioning system into a single integrated rotating device. By merging these functions into one mechanism, the overall device complexity is managed more efficiently than if separate devices were used for each function.

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system reduces operator exposure to blood samples, provides quick and accurate ESR measurements, and improves operational efficiency while maintaining reliability and accuracy comparable to the Westergren method.

Implementation Method 1

infrared transmitting and receiving devices... infrared rays penetrate through the closed containers to realize detecting

Methodology Applied
Scientific EffectInfrared radiation: Infrared Radiation

Implementation Method 2

The rotating device is connected to the rotating shaft, and drives the rotating shaft to rotationally drive the sample rack to turn over up and down

Methodology Applied
Scientific EffectCentrifugal force: Centrifugal Force

Implementation Method 3

Erythrocyte sedimentation rate (ESR) is a sedimentation velocity of the erythrocyte in a unit time

Methodology Applied
Scientific EffectGravitation: Gravitation

Data Source

PatentUS9733175B2Full-automatic erythrocyte sedimentation rate analysis meter and detecting method thereof
Publication Date: 2017.08.15 SHENZHEN YHLO BIOTECH
  • US9733175B2 patent drawing
  • US9733175B2 patent drawing
  • US9733175B2 patent drawing

AI summary

The invention provides a full-automatic erythrocyte sedimentation rate analyzer, which comprises a base as well as a blending device and a detecting device mounted on the base, wherein the blending device comprises a sample rack, a sample rack bracket and a rotating device; the sample rack bracket is arranged on the base, and is connected to the sample rack through a rotating shaft; more than one test tube rack is arranged on the sample rack; the rotating device is connected to the rotating shaft, and drives the rotating shaft to rotationally drive the sample rack to turn over up and down; a plurality of holes are arranged in each test tube rack; a fixing device is arranged in the hole, and used for placing and fixing a closed container containing samples; the detecting device comprises a guide device, a driving device, infrared transmitting and receiving devices having the same quantity as that of the test tube racks, and a mounting rack; the driving device drives the mounting rack to move up and down along the guide device; the mounting rack drives the infrared transmitting and receiving devices to move; the closed containers containing the samples are located on moving paths of the infrared transmitting and receiving devices; and infrared rays penetrate through the closed containers to realize detecting.