Essential Oil Blend with Polyionic Enhancers for Antimicrobial Efficacy

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Solution Overview

Problem

There is a need to enhance the cellular uptake and antimicrobial effectiveness of plant essential oils to improve their bacterial-fighting capabilities, particularly in veterinary and human applications, where existing single essential oils may not be sufficient.

Innovation Solution

A combination of plant essential oils, preferably including oregano oil, is blended with a small amount of polyionic organic or inorganic enhancers and used in disinfecting compositions like teat dips or scours treatments, along with microencapsulation to extend activity throughout the gastrointestinal tract.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If a single plant essential oil is used, then the composition is simple and easy to manufacture, but the antimicrobial effectiveness is insufficient

Engineering Contradiction:
Improveantimicrobial effectivenessVSAvoidcomposition complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent combines multiple plant essential oils (at least two different essential oils) into a blend to achieve enhanced antimicrobial effectiveness. The combination of oils creates a synergistic effect that improves bacterial-fighting capability compared to using a single oil, while maintaining relative simplicity in the composition structure.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The invention uses composite material principles by creating an essential oil blend composed of multiple different oils rather than a single pure oil. This composite approach leverages the complementary properties of different essential oils to achieve superior antimicrobial activity while maintaining the natural characteristics of the composition.

Inventive Principle:
Principle #40Composite materials

2Reliability

If essential oils are used without enhancers, then the composition is simple, but cellular uptake and antimicrobial effect are limited

Engineering Contradiction:
Improveantimicrobial effectVSAvoidcomposition complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent introduces enhancers as intermediary substances that facilitate the cellular uptake of essential oil components. These enhancers act as mediators between the essential oils and bacterial cells, improving penetration and absorption of the antimicrobial compounds into bacterial cells to enhance the overall antimicrobial effect.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The invention modifies the composition parameters by adding enhancers to the essential oil blend. This parameter change (adding enhancer components) alters the physical and chemical properties of the composition to improve cellular permeability and uptake, thereby enhancing antimicrobial effectiveness without fundamentally changing the core essential oil components.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If essential oils are used for gastrointestinal tract treatment, then therapeutic effectiveness is improved, but the duration of action is limited

Engineering Contradiction:
Improvetherapeutic effectivenessVSAvoidduration of action
Core Design Contradiction:
ReliabilityVSDuration of action of moving object

Solution Approach 1:

The patent employs microencapsulation as a preliminary action to protect and deliver essential oils through the gastrointestinal tract. The microencapsulated form allows the essential oils to survive the harsh gastric environment and be released at the appropriate location, extending the duration of action and improving therapeutic effectiveness for gastrointestinal infections.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The combination of essential oils with enhancers significantly increases antimicrobial effectiveness, as demonstrated by improved treatment outcomes in veterinary and human applications, including effective treatment of gastrointestinal infections, with enhanced absorption and localized activity.

Implementation Method 1

Some researchers have theorized that plant essential oils soften the walls of the bacteria then permeate them thus causing an enhanced anti-bacterial effect

Methodology Applied
Scientific EffectPermeation: Permeation

Implementation Method 2

There is a continuing need for increasing the cellular uptake of plant essential oils in order to enhance their anti-bacterial effect

Methodology Applied
Scientific EffectAbsorption: Absorption (physical)

Data Source

PatentUS8173182B2Enhanced antimicrobial activity compositions of blends of plant essential oils
Publication Date: 2012.05.08 ALGOSTREAM INC

AI summary

Antimicrobial compositions based on a combination or blend of plant essential oils is of enhanced antimicrobial effectiveness; by adding to the combination of at least two plant essential oils, and preferably adds a small but antimicrobial enhancing effective amount of an enhancer selected from the group consisting of polyionic organic enhancers and polyionic inorganic enhancers. One preferred blended oil composition is a mixture of plant essential oils wherein at least one of the oils is oregano oil. The oil blend is used as a major component in the finished product anti-microbial.