Esterified Creatine and Betaine Antivirals for Hyper-Inflammation
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Existing treatments for coronavirus and influenza infections fail to adequately reduce inflammatory responses and enhance immune support, leading to exacerbated recovery and potential death due to hyper-inflammation.
Innovation Solution
Administering antiviral therapeutic compounds such as creatine esters and betaine esters, which enhance solubility and permeability, reducing inflammatory responses and boosting immune defense against viruses.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Object-affected harmful factors
If conventional treatments are used for coronavirus and influenza infections, then the treatments are available and easy to administer, but they fail to adequately reduce inflammatory responses and enhance immune support, leading to exacerbated recovery and potential death due to hyper-inflammation
Solution Approach 1:
The patent modifies the chemical structure of creatine and betaine by introducing ester groups with varying chain lengths and configurations. This parameter change in molecular structure optimizes the compounds' ability to reduce inflammation and support immune function, transforming them from conventional supplements to targeted therapeutic agents that effectively address hyper-inflammation in viral infections
Solution Approach 2:
The invention creates composite molecular structures by combining creatine and betaine with various ester groups (cyclohexyl, isopentyl, propylene glycol laurate, glycerol laurate). These composite molecules exhibit enhanced pharmacological properties that simultaneously reduce inflammatory responses and bolster immune support, overcoming the limitations of conventional single-function treatments
2Quantity of substance
If the body synthesizes creatine and betaine under usual conditions, then the body can meet its metabolic needs, but during times of physiologically stressful conditions such as stress, illness or disease, and/or excess exercise, the biosynthesis of these nutrients becomes inadequate
Solution Approach 1:
The esterified creatine and betaine compounds act as intermediary substances that bypass the body's limited biosynthesis capacity. These externally administered compounds serve as mediators that directly supplement the depleted nutrient levels during stress conditions, eliminating the bottleneck in endogenous production without requiring increased biosynthetic activity
Solution Approach 2:
The patent provides pre-formed esterified creatine and betaine compounds that can be immediately utilized by the body upon administration. This preliminary preparation of the compounds in their active esterified forms eliminates the need for the body to synthesize them de novo during critical stress periods, ensuring immediate availability of these essential nutrients
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The compounds effectively reduce inflammation, increase immune support, and enhance survival rates in patients infected with coronaviruses or influenza viruses by optimizing antiviral production and energy availability.
Implementation Method 1
enhance solubility and permeability
Implementation Method 2
enhance solubility and permeability
Data Source
AI summary
Antiviral therapeutic compounds and compositions that may be used in methods of preventing and/or treating infection(s) caused by coronaviruses or influenza viruses.