Tooth Varnish Using Ethyl Cellulose for Fluoride Suspension

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Solution Overview

Problem

Existing tooth varnishes, particularly those containing natural film-forming ingredients like shellac and shellac wax, often exhibit batch-to-batch variability, leading to uneven fluoride application and difficulty in achieving prolonged exposure due to inconsistent rheological properties.

Innovation Solution

A tooth varnish composition comprising a fluoride source, ethyl cellulose, mastic, beeswax, and a non-aqueous solvent, where ethyl cellulose suspends the fluoride source effectively, providing consistent application and prolonged exposure without shellac or shellac wax, and with a low water content.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Duration of action of stationary object

If natural film-forming ingredients such as shellac and shellac wax are used in tooth varnish, then the composition can form a film for prolonged fluoride exposure, but the composition exhibits batch-to-batch variability affecting rheological properties and application uniformity

Engineering Contradiction:
Improveprolonged fluoride exposure timeVSAvoidbatch-to-batch consistency
Core Design Contradiction:
Duration of action of stationary objectVSManufacturing precision

Solution Approach 1:

The patent changes the chemical composition parameters by replacing natural shellac and shellac wax with a synthetic polymer system consisting of polyvinylpyrrolidone (PVP) and carboxymethyl cellulose (CMC). This substitution maintains the film-forming capability for prolonged fluoride exposure while eliminating batch-to-batch variability inherent in natural products, thereby achieving consistent rheological properties across manufacturing batches.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent employs a composite material system combining PVP and CMC in specific proportions (PVP: 0.5-5% w/w, CMC: 0.1-2% w/w). This composite approach leverages the complementary properties of both polymers - PVP provides film-forming ability while CMC contributes to viscosity control and stability - achieving both prolonged exposure and manufacturing consistency.

Inventive Principle:
Principle #40Composite materials

2Duration of action of moving object

If natural film-forming ingredients are used in tooth varnish, then prolonged fluoride contact is achieved, but uneven application and difficulty in applying to tooth surfaces occur due to inconsistent rheological properties

Engineering Contradiction:
Improveprolonged contact timeVSAvoidapplication ease
Core Design Contradiction:
Duration of action of moving objectVSEase of operation

Solution Approach 1:

The patent optimizes rheological parameters by selecting specific polymer concentrations and types. The PVP concentration (0.5-5% w/w) and CMC concentration (0.1-2% w/w) are carefully controlled to achieve optimal viscosity and flow characteristics. This ensures the varnish remains applyable to tooth surfaces while maintaining prolonged contact time after application.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition ensures even suspension and prolonged fluoride exposure, improving the consistency and application of fluoride, reducing phase separation, and maintaining viscosity for effective dental hypersensitivity prevention.

Implementation Method 1

ethyl cellulose in an amount effective to achieve suspension of the fluoride source

Methodology Applied
Scientific EffectSuspension: Suspension

Implementation Method 2

a non-aqueous solvent selected from methanol, ethanol, ethyl acetate, acetone, and isopropanol

Methodology Applied
Scientific EffectSolvation: Solvation

Implementation Method 3

The film that forms upon evaporation of solvent from the tooth surface allows for a longer exposure time

Methodology Applied
Scientific EffectEvaporation: Evaporation

Data Source

PatentEP3071299B1Tooth varnish compositions and methods for their use
Publication Date: 2019.02.20 COLGATE PALMOLIVE CO

AI summary

The disclosure provides hypersensitivity preventative tooth varnish compositions comprising, inter alia, ethyl cellulose and fluoride, and methods for the use of such compositions for the treatment of hypersensitive teeth.