Eurycoma longifolia extract for hormonal imbalance treatment
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Solution Overview
Problem
Current treatments for hormonal imbalance in females, particularly during menopause, are limited and often come with adverse effects, necessitating a safer alternative to alleviate symptoms such as hot flashes, mood swings, and osteoporosis.
Innovation Solution
The use of Eurycoma longifolia extract, which normalizes estrogen, progesterone, follicle stimulating hormone (FSH), and luteinizing hormone (LH) levels by increasing estrogen and progesterone while decreasing FSH and LH, is proposed as a therapeutic approach.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If hormone replacement therapy is used to treat menopausal symptoms, then symptoms such as hot flashes and mood swings are alleviated, but adverse effects and safety concerns arise
Solution Approach 1:
The patent uses Eurycoma longifolia extract as an intermediary substance that mediates hormonal balance indirectly through phytochemicals rather than direct hormone replacement. The extract contains compounds like eurycomanone and quassinoids that act as natural modulators to restore hormonal equilibrium without the direct risks of exogenous hormone therapy.
Solution Approach 2:
The patent employs a natural herbal extract from Eurycoma longifolia as a safer, alternative treatment that can be administered without the long-term safety concerns of synthetic hormone replacement therapy. The extract provides temporary but effective symptom relief through natural compounds that do not carry the same adverse effect profile.
2Ease of operation
If estrogen levels are increased to alleviate menopausal symptoms, then hot flashes and mood swings improve, but the complexity of hormonal regulation increases
Solution Approach 1:
The Eurycoma longifolia extract enables the body's own hormonal regulatory system to function properly again. The phytochemicals in the extract support the body's natural feedback mechanisms, allowing estrogen and other hormones to regulate themselves without external intervention or complex monitoring systems.
Solution Approach 2:
The patent changes the parameter of hormonal regulation from direct hormone supplementation to natural phytochemical modulation. The extract contains compounds that naturally adjust hormonal parameters through biological pathways, simplifying the treatment approach while maintaining effectiveness.
3Reliability
If FSH and LH levels are decreased to restore hormonal balance, then ovarian function improves, but the mechanism of action becomes more complex
Solution Approach 1:
The Eurycoma longifolia extract works through feedback mechanisms where phytochemicals like eurycomanone interact with hormonal pathways to create self-regulating effects. The extract modulates FSH and LH secretion through natural feedback loops involving the hypothalamus-pituitary-ovarian axis, restoring balance without requiring complex external control systems.
Data Source
AI summary
The present invention is directed to a new kind of medicinal value or health care function of Eurycoma longifolia extracts, particularly in the treatment or alleviation symptoms and/or conditions associated to hormonal imbalance in females, including menopause and its related symptoms. In one aspect, the present invention discloses the use of a composition comprising a therapeutically effective amount of Eurycoma longifolia extract in the manufacture of a medicament for the alleviation of symptoms and/or conditions associated to hormonal imbalance in females, including menopause and its related symptoms. The alleviation of the symptoms and/or conditions according to the present invention is characterised by inducing a change in the hormonal contents of estrogen, progesterone, follicle stimulating hormone (FSH) and luteinizing hormone (LH). Also disclosed is the use of a pharmaceutical composition comprising the therapeutically effective amount of Eurycoma longifolia extract.