Eutectic Mixture Melting Point Depression
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Solution Overview
Problem
The high melting points of 12-hydroxystearic acid and butyl methoxydibenzoylmethane make them difficult to formulate in personal care compositions, leading to issues such as re-crystallization and texture destruction due to gellation, especially when incorporated in non-solid forms.
Innovation Solution
A ternary eutectic mixture of butyl methoxydibenzoylmethane, isopropyl myristate, and 12-hydroxystearic acid with a specific weight ratio and concentration, resulting in a lower melting point, which is stable and can be used in personal care compositions to prevent re-crystallization and maintain texture.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If 12-hydroxystearic acid is used in personal care compositions, then beneficial cosmetic effects are achieved, but high melting point causes formulation difficulties and re-crystallization
Solution Approach 1:
The patent applies parameter changes by creating a eutectic mixture that fundamentally alters the melting point parameter of 12-hydroxystearic acid. The eutectic composition of BMDM, IPM, and 12-HSA produces a mixture with a melting point significantly lower than that of pure 12-HSA, enabling the active ingredient to remain in a non-solid state at formulation temperatures and preventing re-crystallization during storage.
Solution Approach 2:
The patent uses composite materials by combining 12-hydroxystearic acid with specific ratios of butyl methoxydibenzoylmethane and isopropyl myristate to form a eutectic mixture. This composite approach creates a new material system with superior properties - the mixture maintains the beneficial cosmetic effects of 12-HSA while achieving lower melting point and improved formulation stability.
2Ease of operation
If 12-hydroxystearic acid is incorporated in non-solid form, then bioavailability and ease of use are improved, but re-crystallization occurs upon storage destroying texture
Solution Approach 1:
The eutectic mixture changes the temperature parameter of 12-hydroxystearic acid by creating a lower melting point system. This parameter change ensures that the active ingredient remains in a non-solid, stable state at storage temperatures, preventing re-crystallization and maintaining both ease of use and texture stability throughout the product lifecycle.
Solution Approach 2:
The patent applies prior cushioning by formulating the eutectic mixture before incorporation into the personal care composition. This pre-formed eutectic system provides a buffer against re-crystallization, cushioning the product against texture degradation by maintaining the non-solid state of 12-hydroxystearic acid during storage and use.
3Ease of manufacture
If elevated temperatures or solvents are used to formulate 12-hydroxystearic acid, then formulation is achieved, but product stability and texture are compromised
Solution Approach 1:
The eutectic mixture fundamentally changes the temperature parameter required for formulation. By creating a mixture with a lower melting point than pure 12-HSA, the system enables formulation at lower temperatures without requiring elevated heat or problematic solvents, thereby maintaining both formulation capability and product stability.
Solution Approach 2:
The patent uses butyl methoxydibenzoylmethane and isopropyl myristate as intermediary substances that facilitate the formulation of 12-hydroxystearic acid. These intermediaries form a eutectic system that lowers the melting point, acting as a mediator that enables stable formulation without requiring extreme temperatures or aggressive solvents that would compromise product stability.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The eutectic mixture lowers the melting point of the components, ensuring stability and preventing re-crystallization, thus maintaining the texture and bioavailability of personal care products.
Implementation Method 1
The present inventors have found that certain mixtures comprising BMDM and isopropyl myristate ('IPM') also including 12-HSA have a lower melting point than BMDM and 12-HSA itself.
Implementation Method 2
A ternary eutectic mixture of butyl methoxydibenzoylmethane, isopropyl myristate, and 12-hydroxystearic acid with a specific weight ratio and concentration, resulting in a lower melting point
Implementation Method 3
Another drawback associated with the high melting point of 12-HSA is that it may re-crystallize upon storage after being incorporated in a personal care product in non-solid form like e.g. in a solvent. Such re-crystallization may cause the undesired gellation of such personal care products thereby destroying the texture thereof.
Data Source
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AI summary
The invention relates to active eutectic mixtures of butyl methoxydibenzoylmethane, isopropyl myristate and optionally 12-hydroxystearic acid, personal care products comprising such active eutectic mixtures, a method for preparing such personal care compositions and a method of applying to human skin such personal care compositions.