Endoluminal Prosthesis With Everted Graft for Simultaneous Valve Deployment

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Solution Overview

Problem

Current endovascular procedures face challenges in simultaneously deploying a stent graft for the ascending aorta and an aortic valve, particularly when an aneurysm has engulfed the main vessel and the aortic valve, requiring sequential and invasive delivery methods that are complex and less effective.

Innovation Solution

A prosthesis system with an expandable stent-graft portion and a flexible graft portion that can be delivered in multiple configurations, allowing for the attachment of a valve and perfusion ports, enabling simultaneous deployment and expansion to address both the ascending aorta and aortic valve through a single delivery system.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If sequential delivery of aortic valve and ascending aorta graft is used, then both components can be deployed, but the procedure becomes complex and requires multiple delivery systems

Engineering Contradiction:
Improvedeployment complexityVSAvoiddelivery system complexity
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The patent combines the aortic valve and ascending aorta graft into a single integrated prosthesis unit. The graft is constructed with a body portion and an upwardly extending portion that integrates the valve structure, allowing both components to be delivered through a single delivery system rather than requiring separate sequential delivery of multiple components.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The single delivery system is designed to deliver multiple functional components (graft body, valve structure, and ascending aorta portion) simultaneously. The prosthesis serves multiple functions - providing both aortic valve replacement and ascending aorta reconstruction - through one unified device that can be deployed in a single procedural step.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Object-affected harmful factors

If traditional endovascular delivery is used, then less invasive approach is achieved, but simultaneous deployment of graft and valve is difficult

Engineering Contradiction:
ImproveinvasivenessVSAvoiddeployment capability
Core Design Contradiction:
Object-affected harmful factorsVSEase of operation

Solution Approach 1:

The patent merges the aortic valve and ascending aorta graft into one integrated prosthesis that can be delivered endovascularly through a single access point. This combination allows the less invasive endovascular approach to simultaneously deploy both the valve and graft components without requiring open surgery or multiple separate procedures.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The graft is divided into functional segments (body portion and upwardly extending portion) that are integrated into a single deliverable unit. This segmentation allows each component to be optimized for its specific function while maintaining the ability to deliver the entire assembly through a single endovascular access route.

Inventive Principle:
Principle #1Segmentation

3Reliability

If open surgery is used for both ascending aorta and aortic valve repair, then complete repair is achieved, but patient risk increases

Engineering Contradiction:
Improverepair completenessVSAvoidpatient risk
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The integrated prosthesis combines aortic valve replacement and ascending aorta reconstruction into a single device that can be deployed endovascularly. This approach achieves complete repair of both structures while avoiding the high risks associated with open surgery, including sternotomy, cardiopulmonary bypass, and prolonged operative time.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent replaces the mechanical open surgical approach with an endovascular delivery system. Instead of requiring open chest surgery and direct surgical manipulation, the prosthesis is delivered through catheter-based techniques, substituting minimally invasive mechanical delivery for traditional open surgical mechanics.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Data Source

PatentEP3654884B1Endoluminal prosthesis
Publication Date: 2023.04.12 COOK MEDICAL TECHNOLOGIES LLC
  • EP3654884B1 patent drawingFigure 1
  • EP3654884B1 patent drawingFigure 2~4
  • EP3654884B1 patent drawingFigure 5~6

AI summary

The present embodiments provide an endoluminal prosthesis having a stent- graft portion with a superior end and an inferior end and a graft portion. The graft portion is attached to the stent-graft portion at a junction, and the graft portion extends inferiorly from the junction in a pre-delivery configuration. In a first delivered configuration, the stent-graft portion is radially expanded, and in a second delivered configuration, the graft portion is everted and moved superiorly relative to the pre-delivery configuration. A valve may be attached to the graft portion when the graft portion is in the pre-delivery configuration. When delivered, the stent-graft portion is deployed first, and the graft portion and attached valve are then moved superiorly, with at least a portion of the graft portion extending superiorly beyond the superior end of the stent-graft portion.