Exercise Glucose Model for Intensity-Independent Insulin Adjustment

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Solution Overview

Problem

Existing models for predicting blood glucose levels in diabetics fail to accurately account for the effects of physical activity, particularly aerobic exercise, leading to increased risks of hypoglycemia due to neglecting exercise intensity, and are complex with numerous parameters difficult to identify.

Innovation Solution

A simplified exercise model that uses two parameters, exercise glucose effectiveness and exercise input, independent of exercise intensity, to predict blood glucose levels, allowing for real-time adjustments in insulin delivery and reducing model complexity.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If complex models with multiple parameters are used to describe exercise effects, then modeling accuracy may improve, but parameter identification becomes difficult and model complexity increases

Engineering Contradiction:
Improvemodeling accuracyVSAvoidmodel complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent extracts only the essential parameter (exercise glucose effectiveness) from complex exercise models, eliminating unnecessary parameters while maintaining predictive accuracy for blood glucose changes during exercise

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent changes the approach from using multiple intensity-dependent parameters to a single parameter (exercise glucose effectiveness) that captures exercise effects across different intensities, simplifying the model while maintaining accuracy

Inventive Principle:
Principle #35Parameter changes

2Reliability

If exercise intensity is included as a parameter, then the model may better predict blood glucose changes, but the number of parameters increases making identification difficult

Engineering Contradiction:
Improveprediction accuracyVSAvoidnumber of parameters
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent creates a universal parameter (exercise glucose effectiveness) that works across different exercise intensities and types, making the model applicable to various exercise scenarios without requiring separate parameters for each condition

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent transforms intensity-dependent exercise effects into a single intensity-independent parameter, allowing the model to predict blood glucose changes during exercise of varying intensities using the same parameter

Inventive Principle:
Principle #35Parameter changes

3Device complexity

If the model neglects exercise effects, then the model remains simple, but the risk of hypoglycemia during exercise increases dramatically

Engineering Contradiction:
Improvemodel simplicityVSAvoidhypoglycemia risk
Core Design Contradiction:
Device complexityVSObject-affected harmful factors

Solution Approach 1:

The patent extracts the critical exercise effect from complex physiological models, isolating the essential parameter (exercise glucose effectiveness) that predicts hypoglycemia risk while maintaining model simplicity

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The model provides feedback about exercise-induced blood glucose changes, enabling timely insulin adjustments to prevent hypoglycemia while keeping the model structure simple

Inventive Principle:
Principle #23Feedback

Data Source

PatentUS12499985B2System and method considering the effect of physical activity on the glucoregulatory system
Publication Date: 2025.12.16 ROCHE DIABETES CARE INC
  • US12499985B2 patent drawing
  • US12499985B2 patent drawing
  • US12499985B2 patent drawing

AI summary

A system and method for considering the effects of aerobic exercise on blood glucose levels for individuals is described. In at least one embodiment of the system of the present disclosure, the system comprises a computing device for generating a prediction of future blood glucose levels for the individual at least partly based on an exercise model, wherein the exercise model is based on parameters that are independent of intensity of the aerobic exercise, and a means for taking an action at least based on the prediction from the exercise model.