Expandable Basket Thrombectomy Device for Residual Clot Retrieval
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Solution Overview
Problem
Current mechanical thrombectomy techniques often leave behind residual clots or fragments due to self-expanding stents compressing during retrieval, and aspiration methods may also fail to remove all obstructions, potentially causing further occlusions in smaller vessels.
Innovation Solution
An intravascular device with an expandable basket that can transition from a collapsed to an expanded configuration to engage and retrieve obstructions, featuring a proximally oriented cavity for capturing clots and a mechanism to prevent distal emboli migration during aspiration.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If a self-expanding stent is used to engage and retrieve a clot, then the stent can be pulled back with the clot, but the stent compresses and collapses when encountering radial resistance during retrieval, leaving behind residual clots or fragments
Solution Approach 1:
The stent is designed to dynamically change its expansion state based on operational requirements. During retrieval, the stent transitions from an expanded configuration to a collapsed configuration, allowing it to maintain engagement with the clot while avoiding compression-induced collapse. This dynamic state change enables complete clot retrieval without leaving residual fragments.
Solution Approach 2:
The stent's radial strength and expansion state are changed as operational parameters. By controlling the expansion parameter, the stent can be maintained in an expanded state during clot engagement to provide sufficient radial force, then collapsed during retrieval to prevent compression failure and enable complete withdrawal with the clot.
2Productivity
If direct aspiration is used to remove a clot, then the clot can be aspirated out of the vessel, but residual clots or fragments may migrate distally and occlude smaller downstream vessels
Solution Approach 1:
A filter device is introduced as an intermediary component between the aspiration catheter and the distal vasculature. The filter captures residual clots and fragments during aspiration, preventing their migration to downstream vessels while allowing complete clot removal through the aspiration process.
Solution Approach 2:
The thrombectomy system is segmented into multiple functional components: the aspiration catheter for clot removal, the filter device for fragment capture, and the stent for engagement. This segmentation allows each component to perform its specific function, with the filter specifically addressing the harmful effect of distal emboli migration.
3Reliability
If a stent is used to engage strongly adhered clots, then the stent can retrieve the clot, but the stent may compress and slide through channels created during delivery, leaving residual clots adhered to the vessel wall
Solution Approach 1:
The stent dynamically transitions between expanded and collapsed configurations to maintain reliable clot engagement while preventing compression-induced sliding. During engagement, the stent remains expanded to provide sufficient radial force against strongly adhered clots, then collapses during retrieval to ensure complete withdrawal without leaving residual fragments.
Data Source
AI summary
The invention relates generally to methods and systems for capturing, filtering, or retrieving obstructions or other particulates from a patient's vasculature. In one aspect, device for retrieving an obstruction from a patient is provided that includes an outer delivery shaft and an expandable basket movable between a collapsed configuration and an expanded configuration. The basket is configured to be in the collapsed configuration during delivery and in the expanded configuration during engagement and retrieval of the obstruction. A proximal end of the basket is configured to be centrally and pivotally coupled to the outer delivery shaft. The proximal end and/or a distal end of the basket is movable relative to each other such that a proximal portion of the expandable basket is invertible toward a distal portion of the basket to form a proximally oriented cavity in the expanded configuration to engage and retrieve the obstruction.