Exsufflation System with Real-Time Flow Feedback Control

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Solution Overview

Problem

Conventional exsufflation systems lack precision and customization in controlling peak expiratory flow rate, as they do not effectively monitor or adjust to individual respiratory characteristics of patients, leading to potentially suboptimal therapy settings.

Innovation Solution

A system comprising a pressure generator and processors that control pressurized airflow to the airway, with modules for determining and adjusting flow metrics to achieve a target expiratory flow rate, allowing for precise customization of exsufflation pressure and insufflation parameters based on real-time monitoring.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional exsufflation systems are used with fixed settings, then the device complexity is low and ease of operation is high, but the manufacturing precision and measurement precision of expiratory flow rate are insufficient

Engineering Contradiction:
Improveexpiratory flow rate measurementVSAvoidsystem complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The system continuously monitors expiratory flow rate during exsufflation and uses this feedback to automatically adjust insufflation parameters (pressure, volume, flow rate) to achieve optimal peak expiratory flow rates. This closed-loop control enables precise measurement and adjustment without requiring complex manual calibration procedures.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent replaces manual trial-and-error adjustment methods with automated electronic control systems that use sensors and processors to precisely control and measure airflow parameters, substituting mechanical adjustment with electronic regulation for higher precision.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Adaptability or versatility

If fixed insufflation settings are used, then the ease of operation is maintained, but the adaptability to individual patient respiratory characteristics is poor

Engineering Contradiction:
Improvecustomization to patient characteristicsVSAvoidoperation simplicity
Core Design Contradiction:
Adaptability or versatilityVSEase of operation

Solution Approach 1:

The system dynamically adjusts insufflation parameters based on real-time monitoring of patient respiratory characteristics and expiratory flow rates. The control system modifies pressure, volume, and flow rate settings during therapy sessions to adapt to changing patient needs, enabling personalized treatment without requiring manual reconfiguration by operators.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system automatically determines optimal insufflation settings by monitoring patient responses and adjusting parameters autonomously, eliminating the need for operators to manually customize settings for each patient while still achieving personalized therapy.

Inventive Principle:
Principle #25Self-service

3Productivity

If trial and error method is used to determine settings, then the device complexity remains low, but the productivity and treatment effectiveness are reduced due to time consumption

Engineering Contradiction:
Improvetreatment efficiencyVSAvoidcontrol system complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The system performs preliminary monitoring of expiratory flow rates during initial insufflation phases to predict optimal settings before full exsufflation begins. This preliminary assessment allows the system to pre-adjust parameters for subsequent cycles, eliminating the need for time-consuming trial-and-error procedures during actual treatment.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

Real-time feedback from flow sensors enables the system to quickly identify effective settings and adjust parameters across treatment cycles, dramatically reducing the time needed to achieve optimal therapy compared to conventional trial-and-error methods while incorporating automated control complexity.

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This system provides more precise and personalized airway clearance therapy by monitoring and adjusting exsufflation flow rates, ensuring effective removal of sputum and debris, improving patient outcomes compared to conventional methods.

Implementation Method 1

A pressure generator is provided and one or more processors are provided and configured to execute computer program modules including a control module. The control module is configured to control the pressure generator such that the pressure of the pressurized flow of breathable gas at the airway of the subject prior to a transition time is at an insufflation pressure level, and such that subsequent to the transition time the pressure level of the pressurized flow of breathable gas at the airway of the subject is at an exsufflation pressure level

Methodology Applied
Scientific EffectPressure gradient: Pressure Gradient

Data Source

PatentEP2654867B1System for inexsufflating a subject
Publication Date: 2020.06.24 KONINKLIJKE PHILIPS NV
  • EP2654867B1 patent drawingFigure 1
  • EP2654867B1 patent drawingFigure 2
  • EP2654867B1 patent drawingFigure 3

AI summary

In order to provide effective inexsufflation to a subject, gas flow out of the lungs of the subject during exsufflation is monitored. One or more of exsufflation pressure, one or more insufflation parameters, and/or parameters of transitions between insufflation and exsufflation can be adjusted in order to maintain gas flow during exsufflation at or near a target level. The one or more insufflation parameters may include an insufflation pressure level, an insufflation volume, an insufflation flow, and/or an insufflation time period. The one or more parameters of transitions between insufflation and exsufflation may include the amount of time it takes to transition from the insufflation pressure level to the exsufflation pressure level, and/or the rate of change in the pressure of the pressurized flow of breathable gas from the insufflation pressure level to the exsufflation pressure level.