External Carotid Biosensing for Non-Invasive Cerebral Blood Flow

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Solution Overview

Problem

Current treatments for Poor Cerebral Blood Flow (CBF) are inadequate, as pharmacological approaches are contraindicated for hypertensive patients, mechanical interventions are inconvenient, and lifestyle modifications are hard to adhere to, leading to a need for an effective and adoptable solution to manage CBF and prevent debilitating dizziness and falls.

Innovation Solution

A wearable biosensing system that non-invasively measures CBF using biometric sensors, processes data to predict CBF parameters, and provides real-time alerts and coaching through audio and visual messages to prevent presyncope, syncope, and falls.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If pharmacological approaches are used to increase blood pressure to reduce Poor Cerebral Blood Flow symptoms, then cerebral blood flow improves, but hypertensive patients face contraindication and safety risks

Engineering Contradiction:
Improvecerebral blood flowVSAvoidcontraindication for hypertensive patients
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent replaces pharmacological intervention with a mechanical/wearable sensing system that monitors cerebral blood flow in real-time. The wearable device detects CBF parameters and provides alerts before presyncope or syncope events occur, enabling mechanical prevention rather than chemical treatment.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent introduces an intermediary wearable monitoring system between the patient and the harmful outcome. This intermediary device detects early signs of CBF deterioration and provides coaching alerts to prevent syncope events, avoiding the need for direct pharmacological intervention that could harm hypertensive patients.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If mechanical interventions such as compression socks or airbag belts are used, then cerebral blood flow improves, but ease of operation deteriorates due to daily inconvenience of donning and doffing

Engineering Contradiction:
Improvecerebral blood flowVSAvoidconvenience of daily use
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The patent replaces bulky mechanical interventions like compression socks and airbag belts with a lightweight wearable sensing device. This new device provides continuous CBF monitoring without requiring the user to don and doff heavy mechanical garments, significantly improving ease of operation while maintaining reliability.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent extracts the essential monitoring function from cumbersome mechanical interventions. Instead of using full-body compression garments or airbag systems, the invention isolates the critical sensing function into a small wearable device that can continuously monitor CBF without the bulk and inconvenience of traditional mechanical interventions.

Inventive Principle:
Principle #2Taking out (Extraction)

3Reliability

If lifestyle modifications such as increased exercise, dietary changes, and slowed transitions are implemented, then cerebral blood flow improves, but ease of operation worsens due to burden of behavior change adherence

Engineering Contradiction:
Improvecerebral blood flowVSAvoidadherence to behavior change
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The patent implements real-time feedback through the wearable device that monitors CBF and provides immediate coaching alerts when parameters indicate risk of presyncope or syncope. This automated feedback system replaces the need for patients to remember and adhere to complex lifestyle modifications, as the device itself provides real-time guidance on when and how to adjust behavior.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent enables the system to serve itself by using automated algorithms to interpret CBF data and generate coaching alerts without requiring patient judgment or memory. The wearable device autonomously monitors parameters, compares them against risk thresholds, and provides appropriate guidance, eliminating the burden of manual behavior change adherence.

Inventive Principle:
Principle #25Self-service

4Ease of operation

If wearable biosensing system is used to non-invasively measure CBF, then ease of operation improves, but measurement precision must be maintained for clinical accuracy

Engineering Contradiction:
Improvenon-invasive wearable measurementVSAvoidaccuracy of CBF parameter
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The patent employs optical sensing mechanisms within the wearable device to detect CBF parameters non-invasively. By using light-based detection methods rather than invasive mechanical or electrical sensors, the system achieves both ease of operation (non-invasive wearable use) and measurement precision (accurate CBF parameter detection).

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system effectively predicts and prevents CBF-related dizziness and falls by providing immediate alerts and coaching, enhancing user adherence and safety, particularly for the elderly.

Implementation Method 1

obtain, using the biometric sensor, biometric data relating to a blood flow waveform of one or more arteries near the target location

Methodology Applied
Scientific EffectPhotoplethysmography: Absorption (EM radiation)

Data Source

PatentUS20250380924A1Systems and Methods for Non-Invasively Inferring Cerebral Blood Flow From the External Carotid Artery
Publication Date: 2025.12.18 LUMIA HEALTH INC
  • US20250380924A1 patent drawing
  • US20250380924A1 patent drawing
  • US20250380924A1 patent drawing

AI summary

The disclosed system provides a non-invasive method for measuring blood flow to the brain. It comprises a biometric sensor configured to be removably retained against an external surface of a skin portion of a target location of a user, and a processor and a memory storing computer instructions. The system obtains biometric data relating to a blood flow waveform of one or more arteries near the target location, determines a parameter indicative of a blood flow to the brain of the user based on the biometric data, and displays or transmits the parameter. The determination of the parameter involves performing computations using the biometric data and/or the blood flow waveform.