External Electrode Cardiac Dispersion Metrics for Noninvasive Pacing Assessment
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Solution Overview
Problem
Current methods for determining the benefit of cardiac conduction system therapy in patients are invasive and require implantable devices, lacking noninvasive screening options to assess cardiac conduction system pacing therapy before implantation.
Innovation Solution
The use of external electrodes to measure cardiac electrical activity and generate electrical heterogeneity information, such as metrics of dispersion in cardiac electrical activation times, to determine whether cardiac conduction system pacing therapy would benefit a patient without the need for implantable devices.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If implantable devices are used to determine cardiac conduction system therapy benefit, then measurement precision is improved, but device complexity and invasiveness increase
Solution Approach 1:
The patent uses external electrodes as an intermediary tool to measure cardiac electrical activation times without requiring implantable devices. The external electrodes capture electrical signals from the body surface, which are then processed to determine activation times and assess therapy benefit, thereby avoiding the need for invasive implantation while maintaining measurement capability
Solution Approach 2:
The patent creates a surrogate measurement system using external electrodes that copies the function of implantable devices. By measuring electrical potentials at body surface locations and calculating activation times from these external measurements, the system replicates the measurement capability of invasive devices without the associated complexity and invasiveness
2Measurement precision
If implantable devices are used to determine cardiac conduction system therapy benefit, then measurement precision is improved, but ease of operation deteriorates
Solution Approach 1:
External electrodes serve as a noninvasive intermediary that simplifies the assessment process. The electrodes can be easily applied to the patient's skin without surgical intervention, making the procedure more accessible and easier to perform while still providing the necessary electrical measurements for therapy evaluation
Solution Approach 2:
The patent replaces the mechanical implantation process with a noninvasive external measurement system. Instead of surgically implanting devices to measure cardiac electrical activity, the system uses external electrodes and computational algorithms to achieve the same assessment goal, eliminating the need for surgical procedures and complex implantation protocols
Data Source
AI summary
Determination of cardiac conduction system pacing therapy benefit may be performed by the systems, methods, devices, and interfaces described herein. For example, various metrics of activation time dispersion may be generated based on electrical activity monitored by a plurality of external electrodes such as, e.g., a left-sided metric of dispersion and a global metric of dispersion. Such various metrics of activation time dispersion may be used to determined whether cardiac conduction system pacing would be beneficial.