Extrusion Device for Microalgae Cell Disruption

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Solution Overview

Problem

Existing methods for disrupting microalgae cell walls, such as high-pressure homogenization, are energy-intensive and economically unviable for large-scale biofuel production, and do not efficiently adjust to different microalgae species and sizes.

Innovation Solution

A device and method for mechanical disruption of microalgae cells using extrusion at low pressures (76.5 to 153.0 kgf/cm2 or 75 to 150 bar), with an adjustable annular channel to accommodate different microalgae species and sizes, and a cooling system to maintain physicochemical properties of extracted materials.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If high-pressure homogenization is used for cell disruption, then extraction yield is improved, but energy consumption increases

Engineering Contradiction:
Improveextraction yieldVSAvoidenergy consumption
Core Design Contradiction:
ProductivityVSUse of energy by moving object

Solution Approach 1:

The invention changes the pressure parameter from high (300-1500 bar) to low (75-150 bar) while maintaining effective cell disruption through a different mechanism (extrusion through annular channel with adjustable gap), thereby reducing energy consumption while preserving extraction yield

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The invention replaces the traditional high-pressure homogenization mechanical system with an extrusion-based system that uses an annular channel and adjustable gap mechanism, substituting extreme pressure with a controlled extrusion process that achieves cell disruption at lower energy input

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Reliability

If standard homogenization equipment is used, then cell disruption is achieved, but adaptability to different microalgae species is poor

Engineering Contradiction:
Improvecell disruption effectivenessVSAvoidadaptability to different microalgae species
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The invention introduces dynamic adjustability through the annular channel gap control mechanism, allowing the system to adapt its geometry to different microalgae species and cell sizes, thereby maintaining reliable cell disruption across diverse organisms

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The extrusion device with adjustable annular channel serves as a universal platform that can process multiple microalgae species with different cell characteristics, replacing specialized high-pressure homogenizers with a single adaptable system

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Productivity

If high pressure is applied for cell disruption, then extraction efficiency is improved, but operating costs increase

Engineering Contradiction:
Improveextraction efficiencyVSAvoidoperating costs
Core Design Contradiction:
ProductivityVSLoss of energy

Solution Approach 1:

The invention changes the operating pressure parameter from high to low range while maintaining extraction efficiency through optimized extrusion geometry and adjustable gap, directly reducing energy-related operating costs

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The method achieves efficient cell disruption with reduced energy consumption, allowing for regulation based on microalgae species and size, and preserves the quality of extracted materials by maintaining low temperatures.

Implementation Method 1

mechanical disruption of cells of microorganisms by extrusion, using low pressures from 76.5 to 153.0 kgf/cm2 (75 to 150 bar)

Methodology Applied
Scientific EffectCompression: Compression

Implementation Method 2

The mechanisms of cell disruption by the homogenizer are not completely understood but have been attributed to pressure variation, shear stress, inertial forces, shock, turbulence and cavitation

Methodology Applied
Scientific EffectShear stress: Shear Stress

Implementation Method 3

a cooling system to avoid loss of physicochemical properties of the material extracted by cell disruption

Methodology Applied
Scientific EffectHeat exchange: Heat Exchanger

Data Source

PatentUS12270021B2Device and method for microorganism cell disruption by extrusion
Publication Date: 2025.04.08 PETROLEO BRASILEIRO SA PETROBRAS
  • US12270021B2 patent drawing
  • US12270021B2 patent drawing

AI summary

Aspects are provided in relation to devices and systems for microorganism cell wall disruption. In this scenario, a device is provided for cell disruption of a microorganism suspension comprising (i) an inlet duct (1) of microorganisms, (ii) an annular channel (13) downstream of inlet duct (1) and in communication therewith, adapted for disruption of microorganism cells, the annular channel (13) being formed by an external part (7) and an internal part (8), the internal part being positioned inside the cavity formed by the external part (7) and (iii) an outlet duct (9) downstream of annular channel (13) and in communication therewith, for output of the ruptured microorganisms. A method is further provided that is associated with the device described above.