Eye Electroporation Needle Insertion With Spherical Support Stabilization

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Existing electroporation devices face issues with needle insertion into the eye, as the impact of the needle can cause eye rotation, and clamps for stabilization are bulky and require additional operator assistance.

Innovation Solution

A device with a support base and combs that compress the eye during needle insertion, using a spherical contact surface and aligned needles to stabilize the eye, allowing single-operator insertion.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If needles are inserted tangentially to the eye surface, then insertion precision is improved, but eye rotation occurs during insertion

Engineering Contradiction:
Improveinsertion precisionVSAvoideye stability
Core Design Contradiction:
Manufacturing precisionVSStability of the object's composition

Solution Approach 1:

The device applies preliminary compression force to the eye surface before needle insertion to prevent rotation. The compression element presses against the eye surface in advance, creating stabilizing pressure that counteracts the rotational tendency caused by tangential needle insertion, thereby maintaining eye stability during the insertion process

Inventive Principle:
Principle #9Preliminary anti-action

2Stability of the object's composition

If clamps are used to maintain the eye, then eye stability is improved, but device complexity and operator requirements increase

Engineering Contradiction:
Improveeye stabilityVSAvoiddevice complexity
Core Design Contradiction:
Stability of the object's compositionVSDevice complexity

Solution Approach 1:

The device merges the stabilization function into the support structure itself. The support base with its spherical contact surface and compression element integrates both support and stabilization functions, eliminating the need for separate clamp mechanisms and reducing overall device complexity while maintaining eye stability

Inventive Principle:
Principle #5Merging (Combining)

3Stability of the object's composition

If clamps are used to maintain the eye, then eye stability is improved, but ease of operation deteriorates

Engineering Contradiction:
Improveeye stabilityVSAvoidease of operation
Core Design Contradiction:
Stability of the object's compositionVSEase of operation

Solution Approach 1:

The device achieves self-stabilization through its geometric design. The spherical contact surface of the support base naturally conforms to the curvature of the eye, and the compression element automatically applies stabilizing pressure without requiring additional operators or complex adjustment mechanisms, thereby improving ease of operation

Inventive Principle:
Principle #25Self-service

Data Source

PatentEP3730102B1Needle insertion device for the electroporation of a product into an eye
Publication Date: 2025.07.09 PULSESIGHT THERAPEUTICS
  • EP3730102B1 patent drawingFigure 1
  • EP3730102B1 patent drawingFigure 2~3
  • EP3730102B1 patent drawingFigure 4~5b

AI summary

The present invention relates to a device comprising: - a support (4) comprising a support base (10) defining - a spherical base contact surface (18), extending along a virtual sphere (S) and - a circular rim (20) extending in a rim plane (P20); - a first and a second needle (8a;8b) mobile on the support between extracted and inserted positions in which the first and second needles are outside and maximally inserted in said virtual sphere, respectively, via first and second intermediate piercing positions in which, respectively, the first and second needles extend along first and second insertion axis (Δ8a;Δ8b) and their tips are located on first and second insertion points (M8a;M8b) belonging respectively to first and second hemispheres of the virtual sphere separated by a "median radial plane of the rim", an angle (θ) between the median radial plane and any insertion axis being between 70° and 110°.