Eye Imaging Workflow for Early Microvascular Risk Assessment

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Solution Overview

Problem

Patients with diseases such as sepsis or coronavirus often exhibit mild symptoms initially, but can rapidly deteriorate due to endothelial cell malfunction and microvascular problems, which are not easily detected by conventional vital sign monitoring.

Innovation Solution

An eye imaging device with a camera and computing system that captures eye images, determines a workflow based on a risk score, conducts a microvascular assessment, and adjusts the risk score accordingly, allowing for patient self-use without mydriatic drugs.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional vital sign monitoring is used, then patient monitoring is simple and accessible, but microvascular changes cannot be detected early

Engineering Contradiction:
Improvedetection of microvascular changesVSAvoideye imaging device
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The eye imaging device is designed to perform multiple functions: capturing eye images, conducting microvascular assessments, calculating risk scores, and providing clinical decision support. This multi-functionality allows a single device to address both the need for early microvascular detection and maintain broad applicability across different patient scenarios.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The system enables patient self-monitoring through automated workflows where the device captures images, processes them through AI algorithms, and generates risk assessments without requiring constant clinician intervention. This reduces the complexity burden on healthcare providers while maintaining high measurement precision.

Inventive Principle:
Principle #25Self-service

2Ease of operation

If eye imaging device is made accessible to patients for self-use, then clinician exposure is reduced, but workflow complexity increases

Engineering Contradiction:
Improvepatient self-useVSAvoidworkflow determination
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The system pre-determines workflows based on patient risk scores before image capture. By calculating initial risk assessments and selecting appropriate imaging protocols in advance, the device simplifies the actual patient operation while maintaining complex adaptive capabilities through automated decision-making algorithms.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The workflow determination is dynamic and adapts based on patient-specific risk factors. The system adjusts imaging parameters and assessment protocols automatically according to the calculated risk score, enabling patient self-use without requiring them to understand complex procedures while maintaining optimized diagnostic workflows.

Inventive Principle:
Principle #15Dynamics

3Measurement precision

If comprehensive microvascular assessment is performed, then risk scoring accuracy is improved, but assessment time increases

Engineering Contradiction:
Improverisk score accuracyVSAvoidassessment time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system performs microvascular assessments selectively based on patient risk scores. For low-risk patients, simplified assessments are used, while high-risk patients receive comprehensive evaluations. This partial action approach maintains high risk score accuracy for those who need it while reducing unnecessary assessment time for lower-risk individuals.

Inventive Principle:
Principle #16Partial or excessive action

Solution Approach 2:

Manual comprehensive assessments are replaced with automated AI-based image analysis. The system uses machine learning algorithms to rapidly process eye images and extract microvascular features, achieving comprehensive assessment accuracy without the time cost of manual evaluation by clinicians.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Data Source

PatentUS12369794B2Microvascular assessment using eye imaging device
Publication Date: 2025.07.29 WELCH ALLYN INC
  • US12369794B2 patent drawing
  • US12369794B2 patent drawing
  • US12369794B2 patent drawing

AI summary

A system for capturing one or more eye images includes an eye imaging device having a camera configured to capture the eye images. The system determines a workflow for capturing the eye images using the eye imaging device. The workflow is determined based on a risk score for a given patient. The system performs the workflow on the eye imaging device to capture the eye images, conducts a microvascular assessment based on the captured eye images, and adjusts the risk score based on the microvascular assessment.