Sterilization Filter Unit F-Value Control for Lower Heat Load

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Solution Overview

Problem

Sterilization filter units in aseptic filling machines deteriorate due to high heat exposure from steam or hydrogen peroxide gas, reducing their service life, and there is a need for a method to minimize heat load and extend their lifespan.

Innovation Solution

Implement F-value control for sterilization using heated steam, combined with targeted use of hydrogen peroxide gas, to manage sterilization time and temperature effectively, reducing exposure to high heat and extending the service life of the filter units.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If sterilization filter unit is sterilized by heated steam or gasified hydrogen peroxide, then sterilization effect is achieved, but resin parts deteriorate due to high heat exposure and service life decreases

Engineering Contradiction:
Improvesterilization effectVSAvoidservice life of filter unit
Core Design Contradiction:
ReliabilityVSDuration of action of stationary object

Solution Approach 1:

The patent applies F-value control to precisely manage sterilization parameters (temperature and time) by calculating and controlling the integral of log(killing rate) over time. This allows achieving effective sterilization while minimizing heat exposure duration, thereby protecting resin components from thermal deterioration and extending filter unit service life.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent implements feedback control by measuring temperature at multiple locations during sterilization and using these measurements to calculate F-values. The system adjusts sterilization parameters based on actual temperature data to ensure sterilization effectiveness while preventing excessive heat exposure that would damage resin parts.

Inventive Principle:
Principle #23Feedback

2Reliability

If sterilization time and temperature are increased to ensure sterilization effectiveness, then sterilization reliability improves, but heat load on resin parts increases and service life decreases

Engineering Contradiction:
Improvesterilization effectivenessVSAvoidheat load on resin parts
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent uses F-value control to optimize the sterilization parameter combination (temperature-time profile) to achieve the minimum necessary sterilization effectiveness. By precisely controlling parameters rather than using excessive values, the system reduces heat load on resin components while maintaining sterilization reliability.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent applies partial action by using F-value control to determine the minimum necessary sterilization exposure. Instead of applying excessive heat and time, the system calculates and applies only the necessary sterilization dose (F-value) to achieve effectiveness, thereby reducing harmful heat exposure on resin parts.

Inventive Principle:
Principle #16Partial or excessive action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The method reduces sterilization time and heat exposure, thereby prolonging the service life of sterilization filter units and maintaining aseptic conditions in aseptic filling machines.

Implementation Method 1

The piping for the compressed aseptic air and the sterilization filter unit are typically sterilized by heated steam

Methodology Applied
Scientific EffectThermal energy transfer: Conduction (thermal)

Implementation Method 2

a hydrogen peroxide solution is sprayed and then heated for gasification, and the resulting hydrogen peroxide gas is fed to a sterilization filter unit

Methodology Applied
Scientific EffectEvaporation: Evaporation

Implementation Method 3

hydrogen peroxide is supplied into air piping, and the hydrogen peroxide deposited in the piping is evaporated and fed to a filter by heated air

Methodology Applied
Scientific EffectDecomposition: Decomposition (biological)

Data Source

PatentEP3721908B1Method and apparatus for sterilizing sterilization filter unit
Publication Date: 2025.10.01 DAI NIPPON PRINTING CO LTD
  • EP3721908B1 patent drawingFigure 1~2
  • EP3721908B1 patent drawingFigure 3
  • EP3721908B1 patent drawingFigure 4~5

AI summary

To sterilize a sterilization filter unit with heated steam, minimize the heat load on the sterilization filter unit and extend the service life of the sterilization filter unit. Heated steam is supplied to a sterilization filter unit that sterilizes supplied air, the temperature of the heated steam discharged from the sterilization filter unit is measured at predetermined time intervals, the F value is calculated from the measured temperature, and sterilization of the sterilization filter unit is ended when the F value reaches a target value.