Composite comprising fabric and polyampholyte hydrogel and preparation method thereof

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Solution Overview

Problem

Current materials for ACL reconstruction and high-toughness applications, such as bandages and bullet-proofing, face challenges with mechanical properties, brittleness, and rejection issues due to lack of flexibility and compatibility with the body, while existing composite materials often lack hydrogel components that are both flexible and tear-resistant.

Innovation Solution

A composite comprising a fabric coated with a polyampholyte hydrogel, where the hydrogel is synthesized through random polymerization of cationic and anionic monomers, providing a flexible and tear-resistant material with self-healing properties, suitable for medical and protective applications.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Strength

If carbon fiber is used as a replacement material for ACL reconstruction, then the stiffness and load support capability are improved, but the material causes fracture, fraying, spreading, irritation, poor healing, and accumulation in lymph nodes

Engineering Contradiction:
ImprovestiffnessVSAvoidfracture, fraying, spreading, irritation, poor healing
Core Design Contradiction:
StrengthVSObject-affected harmful factors

Solution Approach 1:

The patent combines carbon fiber with hydrogel to create a composite material that maintains the high stiffness and load-bearing capability of carbon fiber while the hydrogel coating provides biocompatibility, reduces irritation, and prevents harmful effects on surrounding tissues. This composite structure allows the carbon fiber to fulfill its mechanical support function without causing the harmful effects associated with neat carbon fiber implants.

Inventive Principle:
Principle #40Composite materials

2Adaptability or versatility

If hydrogels are used as ligament replacements, then the flexibility and biocompatibility are improved, but the mechanical properties are insufficient to support high loads

Engineering Contradiction:
ImproveflexibilityVSAvoidmechanical properties
Core Design Contradiction:
Adaptability or versatilityVSStrength

Solution Approach 1:

The patent creates a composite where hydrogel is combined with carbon fiber to achieve both flexibility and high mechanical strength. The hydrogel provides flexibility and biocompatibility while the carbon fiber reinforcement ensures the composite can support high loads required for ligament reconstruction, overcoming the limitations of neat hydrogel alone.

Inventive Principle:
Principle #40Composite materials

3Object-affected harmful factors

If traditional hydrogels are used for fabric composites, then the non-toxicity and wound healing promotion are improved, but the brittleness prevents market entry

Engineering Contradiction:
Improvenon-toxicityVSAvoidbrittleness
Core Design Contradiction:
Object-affected harmful factorsVSStrength

Solution Approach 1:

The patent modifies the physical and chemical parameters of the hydrogel through composite formation with carbon fiber, transforming it from a brittle material to a tough, flexible composite. This parameter change maintains the non-toxic and wound-healing-promoting properties of the hydrogel while eliminating the brittleness that prevented commercial application.

Inventive Principle:
Principle #35Parameter changes

4Strength

If fabric composites are used for high strength and toughness applications, then the strength and toughness are improved, but the materials lack flexibility and flexibility-related properties

Engineering Contradiction:
Improvestrength and toughnessVSAvoidflexibility
Core Design Contradiction:
StrengthVSAdaptability or versatility

Solution Approach 1:

The patent creates a fabric-hydrogel composite where the fabric provides strength and toughness while the hydrogel imparts flexibility and elasticity. This composite structure enables the material to simultaneously achieve high mechanical strength and the flexibility needed for applications like bandages and wearable protective gear.

Inventive Principle:
Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composite exhibits significantly enhanced toughness and flexibility, with tear strength greater than individual components, and is biocompatible, making it suitable for ACL reconstruction, bandages, and other high-toughness applications without causing bodily rejection.

Implementation Method 1

the polyampholyte hydrogel is synthesized through random polymerization of cationic and anionic monomers

Methodology Applied
Scientific EffectRandom polymerization:

Implementation Method 2

providing a flexible and tear-resistant material with self-healing properties

Methodology Applied
Scientific EffectSelf-healing:

Implementation Method 3

A composite comprising a fabric coated with a polyampholyte hydrogel

Methodology Applied
Scientific EffectHydrogel: Hydrogel

Data Source

PatentEP3183387B1Composite comprising fabric and polyampholyte hydrogel and preparation method thereof
Publication Date: 2019.09.25 UNIV OF MASSACHUSETTS
  • EP3183387B1 patent drawingFigure 1~2
  • EP3183387B1 patent drawingFigure 3~4
  • EP3183387B1 patent drawingFigure 5A~6

AI summary

A composite comprising a fabric and a polyampholyte hydrogel is provided. In the composite, the polyampholyte hydrogel is a hydrogel of a polymer bearing randomly dispersed cationic and anionic repeat groups and at least a part of the fabric is coated with the polyampholyte hydrogel. A method of preparation of the composite comprises steps (a) to (c): (a) providing a monomer mixture for preparation of a polyampholyte hydrogel; (b) immersing a fabric in the monomer mixture solution; and (c) polymerizing monomers in the monomer mixture solution to obtain a precursor of the composite.