Fatty Acid Ester Plasticizers for Animal Parasite Control Mouldings

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Existing active compound-containing moulded bodies for controlling parasites in animals rely on phthalic esters, which are toxicologically hazardous and environmentally contaminating, and often lead to demixing with polyolefin or vinyl resin matrices, impairing their physicochemical properties and long-term activity.

Innovation Solution

Employing fatty acid esters of polyhydric alcohols, such as di- and triglycerides or propylene glycol esters, which are polar compounds compatible with nonpolar polyolefin and vinyl resin matrices, enhancing the migration of active compounds and maintaining or improving the physicochemical properties of the moulded bodies.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If phthalic esters are used as additives in polyolefin or vinyl resin matrices, then the moulded bodies can be produced with good processability, but the moulded bodies exhibit toxicological hazards and environmental contamination

Engineering Contradiction:
ImproveprocessabilityVSAvoidtoxicological hazards
Core Design Contradiction:
Ease of manufactureVSObject-affected harmful factors

Solution Approach 1:

The patent removes phthalic esters from the formulation entirely and replaces them with fatty acid esters of polyhydric alcohols (such as diglycerides, triglycerides, or propylene glycol esters). This extraction of the harmful substance while maintaining the functional requirements resolves the contradiction between ease of manufacture and toxicological safety.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The invention changes the chemical parameter of the ester additive from phthalic esters to fatty acid esters with specific chain lengths (C6-C18). This parameter change maintains the desired processability and physicochemical properties while eliminating the toxicological and environmental problems associated with phthalates.

Inventive Principle:
Principle #35Parameter changes

2Stability of the object's composition

If polar compounds are combined with nonpolar plastics, then the compatibility should be poor, but the patent achieves good compatibility and prevents demixing

Engineering Contradiction:
ImprovecompatibilityVSAvoidpolar-nonpolar incompatibility
Core Design Contradiction:
Stability of the object's compositionVSDevice complexity

Solution Approach 1:

The patent selects fatty acid esters with specific chain lengths (C6-C18) that have appropriate polarity characteristics. By carefully controlling the chain length and saturation of the fatty acid component, the invention achieves optimal compatibility between the polar ester additive and nonpolar polyolefin matrix, preventing demixing and phase separation.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The invention creates a composite system where fatty acid esters of polyhydric alcohols are combined with polyolefin or vinyl resin matrices. This composite approach achieves synergistic compatibility, where the specific molecular structure of the fatty acid esters ensures good dispersion and stability within the nonpolar polymer matrix without causing phase separation.

Inventive Principle:
Principle #40Composite materials

3Ease of manufacture

If conventional plasticizers are used to improve processability, then the moulded bodies show good manufacturing properties, but the long-term activity and residual effects are impaired

Engineering Contradiction:
ImproveprocessabilityVSAvoidlong-term activity
Core Design Contradiction:
Ease of manufactureVSDuration of action of moving object

Solution Approach 1:

The patent changes the molecular parameters of the ester additive to achieve the right balance between processability and long-term activity. Fatty acid esters with chain lengths of C6-C18 provide optimal viscosity and migration characteristics, ensuring good manufacturing properties while maintaining sustained release of active compounds for up to nine months.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The invention ensures continuous and sustained migration of active compounds from the polymer matrix over an extended period. The fatty acid esters facilitate a controlled, continuous release mechanism that maintains both good initial processability and prolonged long-term activity, avoiding the rapid depletion seen with conventional plasticizers.

Inventive Principle:
Principle #20Continuity of useful action

4Duration of action of moving object

If the migration of active compounds is increased to improve activity, then the knock-down and residual effects are enhanced, but the physicochemical properties of the polymer matrix are impaired

Engineering Contradiction:
ImproveactivityVSAvoidphysicochemical properties
Core Design Contradiction:
Duration of action of moving objectVSStrength

Solution Approach 1:

The patent optimizes the chain length and structure of the fatty acid ester additive to achieve the perfect balance between active compound migration and matrix integrity. Esters with C6-C18 chain lengths provide sufficient polarity to enhance active compound migration for improved knock-down and residual effects, while maintaining adequate compatibility to preserve the mechanical and physical properties of the polymer matrix.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The use of fatty acid esters improves the processability and long-term activity of the moulded bodies without compromising their physicochemical properties, providing effective and environmentally friendly control of parasites in animals for up to nine months.

Implementation Method 1

These novel ingredients should preferably increase the migration of the active compounds from the polymer matrix

Methodology Applied
Scientific EffectMigration: Diffusion

Implementation Method 2

these fatty acid esters are polar compounds whereas the said polyolefins and vinyl resins are relatively nonpolar plastics

Methodology Applied
Scientific EffectCompatibility: Solvation

Data Source

PatentUS7910122B2Active compound-containing solid moulded bodies for external use against parasites on animals
Publication Date: 2011.03.22 ELANCO ANIMAL HEALTH GMBH
  • US7910122B2 patent drawing
  • US7910122B2 patent drawing
  • US7910122B2 patent drawing

AI summary

The present invention relates to active compound-containing moulded bodies for external use against parasites on animals.